Technology Process of 4-allyl-4-ethylcyclohex-2-enone
There total 5 articles about 4-allyl-4-ethylcyclohex-2-enone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.67 h / Inert atmosphere; Cooling with ice
1.2: 1.58 h / Inert atmosphere; Cooling with acetone-dry ice; Cooling with ice
2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / -80 - 0 °C / Inert atmosphere
3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / Cooling with acetone-dry ice; Inert atmosphere
3.2: 24 h / Reflux; Inert atmosphere
With
sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide;
In
tetrahydrofuran; hexane; toluene;
DOI:10.15227/orgsyn.069.0055
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene / 18 h / Reflux; Inert atmosphere
2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.67 h / Inert atmosphere; Cooling with ice
2.2: 1.58 h / Inert atmosphere; Cooling with acetone-dry ice; Cooling with ice
3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / -80 - 0 °C / Inert atmosphere
4.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / Cooling with acetone-dry ice; Inert atmosphere
4.2: 24 h / Reflux; Inert atmosphere
With
sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide;
In
tetrahydrofuran; hexane; toluene;
DOI:10.15227/orgsyn.069.0055
- Guidance literature:
-
With
tetrabutylammonium dihydrogen phosphate; sodium bis(2-methoxyethoxy)aluminium dihydride;
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
1.) toluene, RT, 3 d, 2.) ethanol, reflux, 24 h;
DOI:10.1021/jo00280a040