CP21R7(CP21)

Base Information

Chemical Name:CP21R7(CP21)
CAS No.:125314-13-8
Molecular Formula:C19H15N3O2
Molecular Weight:317.347
Hs Code.:
Mol file:125314-13-8.mol

Synonyms:3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)pyrrole-2,5-dione;3-(3-Amino-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione;3-(1-methylindol-3-yl)-4-(3-aminophenyl)-1H-pyrrole-2,5-dione;

Suppliers and Price of CP21R7(CP21)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CP21R7
25mg
$ 825.00

DC Chemicals
CP21(CP21R7) >98%
100 mg
$ 550.00

CSNpharm
CP21R7
100mg
$ 806.00

CSNpharm
CP21R7
50mg
$ 500.00

Crysdot
CP21R7 98+%
25mg
$ 332.00

Crysdot
CP21R7 98+%
50mg
$ 570.00

ChemScene
CP21R7 99.77%
50mg
$ 588.00

ChemScene
CP21R7 99.77%
100mg
$ 948.00

ChemScene
CP21R7 99.77%
25mg
$ 348.00

ChemScene
CP21R7 99.77%
10mg
$ 192.00

Total 22 raw suppliers

Chemical Property of CP21R7(CP21)

Chemical Property:

Boiling Point:627.4±55.0 °C(Predicted)
PKA:7.79±0.60(Predicted)
PSA：77.12000
Density:1.37±0.1 g/cm3(Predicted)
LogP:3.23770
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Solubility.:insoluble in EtOH; insoluble in H2O; ≥14.25 mg/mL in DMSO

Purity/Quality:

99%, ^*data from raw suppliers

CP21R7 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses CP21R7 is a potent and selective inhibitor of GSK3β.

Technology Process of CP21R7(CP21)

There total 14 articles about CP21R7(CP21) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

TiCI₃: TiCI₃

: 125314-03-6
3-(1-methyl-3-indolyl)-4-(3-nitrophenyl)-1H-pyrrole-2,5-dione

: 125314-13-8
3-(3-aminophenyl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione

Guidance literature:: With sodium hydroxide; In methanol; CH₂Cl₂to; acetone;

Reference yield:

: 3-(3-Amino-phenyl)-4-(1-methyl-1H-indol-3-yl)-furan-2,5-dione

: 125314-13-8
3-(3-aminophenyl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione

Guidance literature:: With ammonium hydroxide; In N,N-dimethyl-formamide; at 140 ℃; for 5h;
DOI:10.1021/jm00079a024

Reference yield:

: 1877-73-2
3-nitro-benzeneacetic acid

: 125314-13-8
3-(3-aminophenyl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂ / 16 h

2: H₂ / 10percent Pd/C / tetrahydrofuran / 16 h / 760 Torr / Ambient temperature

3: 33percent aq. ammonia / dimethylformamide / 5 h / 140 °C

With ammonium hydroxide; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00079a024