Tyrosyl-alanyl-delta-phenylalanyl-glycinamide

Base Information

Chemical Name:Tyrosyl-alanyl-delta-phenylalanyl-glycinamide
CAS No.:97992-01-3
Molecular Formula:C₂₃H₂₉N₅O₅
Molecular Weight:455.514
Hs Code.:
DSSTox Substance ID:DTXSID60243355
Wikidata:Q83127433
Mol file:97992-01-3.mol

Synonyms:TA-delta-Phe-GNH2;Tyr-Ala-delta-Phe-GlyNH2;tyrosyl-alanyl-delta-phenylalanyl-glycinamide

Suppliers and Price of Tyrosyl-alanyl-delta-phenylalanyl-glycinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Tyrosyl-alanyl-delta-phenylalanyl-glycinamide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:920.7°C at 760 mmHg
PKA:9.97±0.15(Predicted)
Flash Point:510.6°C
Density:1.289g/cm³
XLogP3:-0.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:455.21686904
Heavy Atom Count:33
Complexity:674

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)N)NC(=O)C(CC2=CC=C(C=C2)O)N
Isomeric SMILES:C[C@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NCC(=O)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)N

Technology Process of Tyrosyl-alanyl-delta-phenylalanyl-glycinamide

There total 4 articles about Tyrosyl-alanyl-delta-phenylalanyl-glycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78330-94-6
N-Boc-L-tyrosyl-D-alanyl-L-phenylalanyl-glycine

: 78700-75-1,97992-01-3
H-Tyr-D-Ala-Phe-Gly-NH2

Guidance literature:: Multi-step reaction with 2 steps

1: isobutylchloroformate, N-methylmorpholine, NH₃ / tetrahydrofuran / 1.) 1 h, -10 deg C, 2.) 1-2 h, 0-10 deg C

2: aqueous 90percent trifluoroacetic acid, anisole / 0.5 h

With 4-methyl-morpholine; ammonia; methoxybenzene; trifluoroacetic acid; isobutyl chloroformate; In tetrahydrofuran;

Reference yield:

: Boc-Tyr(Bzl)-D-Ala-Phe-Gly-NH₂

: 97412-74-3,97992-01-3
Tyr-D-Ala-Phe-Gly-NH₂

Guidance literature:: Multi-step reaction with 2 steps

1: 10percent Pd/C (HCOONH₄) / methanol; acetic acid / 0.25 h

2: TFA-CH₂Cl₂-anisole (5:4:1) / 0.5 h / Ambient temperature

With Pd/C (HCOONH₄); trifluoroacetic acid; In methanol; acetic acid;
DOI:10.1016/S0040-4039(00)94583-0