4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride

Base Information

Chemical Name:4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride
CAS No.:118269-82-2
Molecular Formula:C₂₃H₂₅ClN₄O*2ClH
Molecular Weight:481.853
Hs Code.:
DSSTox Substance ID:DTXSID80152071

Synonyms:4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride;N-(4-((4-Chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-4-morpholineethanamine dihydrochloride;118269-82-2;C23H25ClN4O.2ClH;DTXSID80152071;LS-92852

Suppliers and Price of 4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride

Chemical Property:

Vapor Pressure:1.09E-15mmHg at 25°C
Boiling Point:628.1°Cat760mmHg
Flash Point:333.7°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:480.125045
Heavy Atom Count:31
Complexity:462

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CCNC2=NN=C(C=C2CC3=CC=C(C=C3)Cl)C4=CC=CC=C4.Cl.Cl

Technology Process of 4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride

There total 6 articles about 4-Morpholineethanamine, N-(4-((4-chlorophenyl)methyl)-6-phenyl-3-pyridazinyl)-, dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70041-47-3
(E)-3-(4-chlorobenzylidene)-5-phenylfuran-2(3H)-one

: 118269-82-2
[4-(4-Chloro-benzyl)-6-phenyl-pyridazin-3-yl]-(2-morpholin-4-yl-ethyl)-amine; hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 2 N NaOH / aq. ethanol / 1 h / Heating

2: hydrazine hydrate / butan-1-ol / Heating

3: POCl₃ / 80 °C

With sodium hydroxide; hydrazine hydrate; trichlorophosphate; In ethanol; butan-1-ol;
DOI:10.1021/jm00123a004

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 118269-82-2
[4-(4-Chloro-benzyl)-6-phenyl-pyridazin-3-yl]-(2-morpholin-4-yl-ethyl)-amine; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: sodium acetate / acetic anhydride / 2 h / 100 °C

2: 2 N NaOH / aq. ethanol / 1 h / Heating

3: hydrazine hydrate / butan-1-ol / Heating

4: POCl₃ / 80 °C

With sodium hydroxide; sodium acetate; hydrazine hydrate; trichlorophosphate; In ethanol; acetic anhydride; butan-1-ol;
DOI:10.1021/jm00123a004

Reference yield:

: 2051-95-8
succinylbenzene

: 118269-82-2
[4-(4-Chloro-benzyl)-6-phenyl-pyridazin-3-yl]-(2-morpholin-4-yl-ethyl)-amine; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: sodium acetate / acetic anhydride / 2 h / 100 °C

2: 2 N NaOH / aq. ethanol / 1 h / Heating

3: hydrazine hydrate / butan-1-ol / Heating

4: POCl₃ / 80 °C

With sodium hydroxide; sodium acetate; hydrazine hydrate; trichlorophosphate; In ethanol; acetic anhydride; butan-1-ol;
DOI:10.1021/jm00123a004