Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate

Base Information

Chemical Name:Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate
CAS No.:126688-00-4
Molecular Formula:C14H21O4P
Molecular Weight:284.292
Hs Code.:
DSSTox Substance ID:DTXSID60560236
Nikkaji Number:J2.164.647D
Mol file:126688-00-4.mol

Synonyms:126688-00-4;Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate;DTXSID60560236

Suppliers and Price of Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:284.11774614
Heavy Atom Count:19
Complexity:313

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C(C)C(=O)CC1=CC=CC=C1)OCC

Technology Process of Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate

There total 4 articles about Diethyl (3-oxo-4-phenylbutan-2-yl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: ((E)-1-Methyl-3-phenyl-2-pyrrolidin-1-yl-propenyl)-phosphonic acid diethyl ester

: 126688-00-4
(1-Methyl-2-oxo-3-phenyl-propyl)-phosphonic acid diethyl ester

Guidance literature:: With oxalic acid; silica gel; In dichloromethane; for 1h; Ambient temperature;
DOI:10.1016/S0040-4039(01)80508-6

Reference yield:

: 78-38-6
ethylphosphonic acid diethyl ester

: 126688-00-4
(1-Methyl-2-oxo-3-phenyl-propyl)-phosphonic acid diethyl ester

Guidance literature:: Multi-step reaction with 4 steps

2: 70 percent / benzene / 2 h / Heating

3: 1.) s-BuLi / 1.) -78 deg C, THF; 2.) from -40 to 25 deg C, 1h

4: 22 percent / 10percent aq. oxalic acid/SiO₂ / CH₂Cl₂ / 1 h / Ambient temperature

With sec.-butyllithium; oxalic acid; silica gel; In dichloromethane; benzene;
DOI:10.1016/S0040-4039(01)80508-6

Reference yield:

: 34403-79-7
diethyl 1-formylethylphosphonate

: 126688-00-4
(1-Methyl-2-oxo-3-phenyl-propyl)-phosphonic acid diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / benzene / 2 h / Heating

2: 1.) s-BuLi / 1.) -78 deg C, THF; 2.) from -40 to 25 deg C, 1h

3: 22 percent / 10percent aq. oxalic acid/SiO₂ / CH₂Cl₂ / 1 h / Ambient temperature

With sec.-butyllithium; oxalic acid; silica gel; In dichloromethane; benzene;
DOI:10.1016/S0040-4039(01)80508-6