3-Methyl-1-phenylbut-2-en-1-amine

Base Information

Chemical Name:3-Methyl-1-phenylbut-2-en-1-amine
CAS No.:127209-35-2
Molecular Formula:C11H15N
Molecular Weight:161.247
Hs Code.:
DSSTox Substance ID:DTXSID901256231
Nikkaji Number:J324.484I

Synonyms:127209-35-2;SCHEMBL563813;DTXSID901256231;AKOS017529255

Suppliers and Price of 3-Methyl-1-phenylbut-2-en-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Methyl-1-phenylbut-2-en-1-amine

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:161.120449483
Heavy Atom Count:12
Complexity:150

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CC(C1=CC=CC=C1)N)C

Technology Process of 3-Methyl-1-phenylbut-2-en-1-amine

There total 1 articles about 3-Methyl-1-phenylbut-2-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1204595-23-2
(1-azido-3-methylbut-2-en-1-yl)benzene

: 127209-35-2
1-amino-1-phenyl-3-methyl-2-butene

Guidance literature:: (1-azido-3-methylbut-2-en-1-yl)benzene; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;

With water; sodium sulfate; In tetrahydrofuran; Inert atmosphere;
DOI:10.1016/j.bmc.2009.11.023

Reference yield: 94.0%

: 127209-35-2
1-amino-1-phenyl-3-methyl-2-butene

: 501-53-1,94274-21-2
benzyl chloroformate

: 1204595-24-3
benzyl (3-methyl-1-phenylbut-2-en-1-yl)carbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.bmc.2009.11.023

Reference yield:

: 127209-35-2
1-amino-1-phenyl-3-methyl-2-butene

: 15325-61-8,1608-28-2,15325-56-1
(E)-(3-methylbut-1-en-1-yl)benzene

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / acetonitrile / Ambient temperature

2: 1.) n-BuLi / 1.) ether, hexane, a) from -78 deg C to -40 deg C, 0.5 h, b) -40 deg C, 0.5 h, 2.) hexane, ether, RT, 2.5 h

3: Pt<<(CH₂=CH)Me₂Si>2O₂> / diethyl ether; xylene / Ambient temperature

4: 99 percent Spectr_. / toluene-d8 / 149 h / 204 °C

With n-butyllithium; Pt Karstedt catalyst; triethylamine; In diethyl ether; ⁽²⁾H₈-toluene; acetonitrile; xylene;
DOI:10.1021/ja00027a028