2-(Ethylamino)-4,5-dihydroxybenzamide

Base Information

Chemical Name:2-(Ethylamino)-4,5-dihydroxybenzamide
CAS No.:127793-87-7
Molecular Formula:C₉H₁₂N₂O₃
Molecular Weight:196.206
Hs Code.:
DSSTox Substance ID:DTXSID20438184
Nikkaji Number:J1.070.912A
Metabolomics Workbench ID:45753
Mol file:127793-87-7.mol

Synonyms:2-(Ethylamino)-4,5-dihydroxybenzamide;127793-87-7;Benzamide, 2-(ethylamino)-4,5-dihydroxy-;DTXSID20438184;CHEBI:165205;3,4-Dihydroxy-6-(ethylamino)benzamide;3,4-dihydroxy-6-(N-ethylamino)benzamid;2-(Ethylamino)-4,5-dihydroxybenzamide, 9CI

Suppliers and Price of 2-(Ethylamino)-4,5-dihydroxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(Ethylamino)-4,5-dihydroxybenzamide

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:196.08479225
Heavy Atom Count:14
Complexity:210

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCNC1=CC(=C(C=C1C(=O)N)O)O

Technology Process of 2-(Ethylamino)-4,5-dihydroxybenzamide

There total 7 articles about 2-(Ethylamino)-4,5-dihydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 172301-58-5
2-[Ethyl-(2,2,2-trifluoro-acetyl)-amino]-4,5-dihydroxy-benzamide

: 127793-87-7
3,4-dihdyroxy-6-(N-ethylamino)benzamide

Guidance literature:: With sodium hydroxide; for 64h; Ambient temperature;

Reference yield:

: 2150-38-1
methyl 3,4-dimethoxybenzoate

: 127793-87-7
3,4-dihdyroxy-6-(N-ethylamino)benzamide

Guidance literature:: Multi-step reaction with 7 steps

1: 72 percent / conc. HNO₃ / 10 - 15 °C

2: 52 percent / HCO₂NH₄ / 10percent Pd/C / methanol / 0.67 h / Ambient temperature

3: 1.) NaBH₄ / 1.) 20 deg C, 2.) 80 deg C, 9 h

4: 40 percent / conc. NH₃ / methanol / 360 h / Ambient temperature

5: 90 percent / pyridine / Ambient temperature

6: 25 percent / BBr₃ / CH₂Cl₂ / -75 - 20 °C

7: 20 percent / 0.2 N aq. NaOH / 64 h / Ambient temperature

With pyridine; ammonium hydroxide; sodium hydroxide; sodium tetrahydroborate; nitric acid; ammonium formate; boron tribromide; palladium on activated charcoal; In methanol; dichloromethane;

Reference yield:

: 26791-93-5
methyl 4,5-dimethoxy-2-nitrobenzoate

: 127793-87-7
3,4-dihdyroxy-6-(N-ethylamino)benzamide

Guidance literature:: Multi-step reaction with 6 steps

1: 52 percent / HCO₂NH₄ / 10percent Pd/C / methanol / 0.67 h / Ambient temperature

2: 1.) NaBH₄ / 1.) 20 deg C, 2.) 80 deg C, 9 h

3: 40 percent / conc. NH₃ / methanol / 360 h / Ambient temperature

4: 90 percent / pyridine / Ambient temperature

5: 25 percent / BBr₃ / CH₂Cl₂ / -75 - 20 °C

6: 20 percent / 0.2 N aq. NaOH / 64 h / Ambient temperature

With pyridine; ammonium hydroxide; sodium hydroxide; sodium tetrahydroborate; ammonium formate; boron tribromide; palladium on activated charcoal; In methanol; dichloromethane;