Tert-butyl (4-chloro-2-methylphenyl)carbamate

Base Information

Chemical Name:Tert-butyl (4-chloro-2-methylphenyl)carbamate
CAS No.:129822-41-9
Molecular Formula:C12H16ClNO2
Molecular Weight:241.718
Hs Code.:
DSSTox Substance ID:DTXSID90563250
Nikkaji Number:J416.449K
Wikidata:Q82447637

Synonyms:tert-butyl (4-chloro-2-methylphenyl)carbamate;129822-41-9;(4-chloro-2-methyl-phenyl)-carbamic acid tert-butyl ester;tert-butyl N-(4-chloro-2-methylphenyl)carbamate;SCHEMBL5731619;DTXSID90563250;XJCFXYCGQPYEJN-UHFFFAOYSA-N;AKOS014476557;tert-butyl 4-chloro-2-methylphenylcarbamate;tert-butyl (4-chloro-2-methyphenyl)carbamate;N-tert-Butoxycarbonyl-4-chloro-2-methylaniline

Suppliers and Price of Tert-butyl (4-chloro-2-methylphenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Tert-butyl (4-chloro-2-methylphenyl)carbamate

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:241.0869564
Heavy Atom Count:16
Complexity:250

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)Cl)NC(=O)OC(C)(C)C

Technology Process of Tert-butyl (4-chloro-2-methylphenyl)carbamate

There total 2 articles about Tert-butyl (4-chloro-2-methylphenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 876353-89-8
tert-butyl (5-chloro-2-methylphenyl)carbamate

: 129822-41-9
(4-chloro-2-methyl-phenyl)-carbamic acid tert-butyl ester

Guidance literature:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 95-69-2
4-chloro-2-methylbenzeneamine

: 129822-41-9
(4-chloro-2-methyl-phenyl)-carbamic acid tert-butyl ester

Guidance literature:: In tetrahydrofuran; Heating;
DOI:10.1055/s-1991-26597 DOI:10.1016/j.bmcl.2005.06.067

Reference yield: 49.0%

: 96388-83-9
2-tetrahydropyranyloxy-1-iodoethane

: 129822-41-9
(4-chloro-2-methyl-phenyl)-carbamic acid tert-butyl ester

: 457622-18-3
3-(2-amino-5-chlorophenyl)-1-propanol

Guidance literature:: 2-tetrahydropyranyloxy-1-iodoethane; (4-chloro-2-methyl-phenyl)-carbamic acid tert-butyl ester; With copper(l) iodide; n-butyllithium; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 17.5h;

With hydrogenchloride; In methanol; water; at 20 ℃; Further stages.;
DOI:10.1021/ol026200s