Acetic acid, diazo-, 3-phenyl-2-propenyl ester, (Z)-

Base Information

• Chemical Name: Acetic acid, diazo-, 3-phenyl-2-propenyl ester, (Z)-
• CAS No.: 130780-62-0
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.213
• Mol file: 130780-62-0.mol

Synonyms:

Chemical Property of Acetic acid, diazo-, 3-phenyl-2-propenyl ester, (Z)-

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetic acid, diazo-, 3-phenyl-2-propenyl ester, (Z)-

There total 1 articles about Acetic acid, diazo-, 3-phenyl-2-propenyl ester, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

(Z)-cinnamyl alcohol (4510-34-3) + 4-acetamidobenzenesulfonyl azide (2158-14-7) + 2,2,6-trimethyl-4H-1,3-dioxin-4-one (5394-63-8) → cis-3-phenyl-2-propen-1-yl diazoacetate (130780-62-0)

Guidance literature:

(Z)-cinnamyl alcohol; 2,2,6-trimethyl-4H-1,3-dioxin-4-one; In tetrahydrofuran; Heating;

4-acetamidobenzenesulfonyl azide; In acetonitrile; at 20 ℃;

With lithium hydroxide;

DOI:10.1016/S0960-894X(02)00793-X

Reference yield: 91.0%

cis-3-phenyl-2-propen-1-yl diazoacetate (130780-62-0) → endo-6-phenyl-3-oxabicyclo<3.1.0>hexan-2-one (88539-24-6,130855-58-2,132435-60-0,132435-61-1,141041-89-6,141506-44-7)

Guidance literature:

With bis(N-tert-butylsalicylaldiminato)copper(II); In toluene; Heating;

DOI:10.1016/S0960-894X(02)00793-X

Reference yield:

cis-3-phenyl-2-propen-1-yl diazoacetate (130780-62-0) → (1R-(1α,5α,6α))-6-phenyl-3-oxabicyclo[3.1.0]hexan-2-one (132435-60-0) + (1S,5R,6S)-6-Phenyl-3-oxa-bicyclo[3.1.0]hexan-2-one (141041-89-6)

Guidance literature:

With trans-Ru^IICl2-(2,6-di-<<(S)-4-isopropyl>oxazol-2-yl>pyridine)-(CH2=CH2); In dichloromethane; Product distribution; Mechanism; other reactant: trans-cinnamyl diazoacetate;

upstream raw materials:

(Z)-cinnamyl alcohol

4-acetamidobenzenesulfonyl azide

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Downstream raw materials:

endo-6-phenyl-3-oxabicyclo<3.1.0>hexan-2-one

(1R-(1α,5α,6α))-6-phenyl-3-oxabicyclo[3.1.0]hexan-2-one

(1S,5R,6S)-6-Phenyl-3-oxa-bicyclo[3.1.0]hexan-2-one

1-(4-morpholinylcarbonyl)-2-(hydroxymethyl)-3-phenylcyclopropane