17-oxoandrosta-5,7-dien-3-yl acetate

Base Information

• Chemical Name: 17-oxoandrosta-5,7-dien-3-yl acetate
• CAS No.: 64110-61-8
• Molecular Formula: C₂₁H₂₈O₃
• Molecular Weight: 328.452
• Mol file: 64110-61-8.mol

Synonyms:5,7-Androstadien-17-one,3b-hydroxy-, acetate (5CI); 3b-Acetoxyandrosta-5,7-dien-17-one;NSC 226158

Chemical Property of 17-oxoandrosta-5,7-dien-3-yl acetate

Chemical Property:

• Vapor Pressure: 2.09E-08mmHg at 25°C
• Boiling Point: 453.3°Cat760mmHg
• Flash Point: 197.4°C
• Density: 1.14g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 17-oxoandrosta-5,7-dien-3-yl acetate

There total 10 articles about 17-oxoandrosta-5,7-dien-3-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

androsta-5,7-diene-3β,17β-diol 3-acetate (124853-32-3) → (3β)-3-Acetoxyandrosta-5,7-dien-17-one (64110-61-8)

Guidance literature:

With PCC on Al; In dichloromethane; for 0.5h;

DOI:10.1006/bioo.1994.1003

Reference yield: 35.0%

C21H29BrO3 → (3β)-3-Acetoxyandrosta-5,7-dien-17-one (64110-61-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1134/S1068162019060396

Reference yield: 33.0%

prasterone acetate (853-23-6) → (3β)-3-Acetoxyandrosta-5,7-dien-17-one (64110-61-8)

Guidance literature:

prasterone acetate; With N-Bromosuccinimide; In cyclohexane; at 70 ℃; for 1h; Reflux;

In 2,4,6-trimethyl-pyridine; 5,5-dimethyl-1,3-cyclohexadiene; at 135 ℃; Reflux;

DOI:10.3390/molecules25051209

upstream raw materials:

7α-bromo-3β-(acetyloxy)androst-5-en-17-one

androsta-5,7-diene-3β,17β-diol 3-acetate

dehydroepiandrosterone

prasterone acetate

Downstream raw materials:

3β-hydroxyandrosta-5,7-diene-17-one

(3β,5Z,7E)-9,10-Secocholesta-5,7,10(19),16-tetraen-23-yne-3,25-diol diacetate