1,3-Benzodioxole-5-acetic acid, 6-benzoyl-

Base Information

Chemical Name:1,3-Benzodioxole-5-acetic acid, 6-benzoyl-
CAS No.:132813-86-6
Molecular Formula:C16H12O5
Molecular Weight:284.268
Hs Code.:
DSSTox Substance ID:DTXSID40473653
Wikidata:Q82303174

Synonyms:1,3-Benzodioxole-5-acetic acid, 6-benzoyl-;132813-86-6;SCHEMBL6754934;DTXSID40473653;2-(6-benzoylbenzo[d][1,3]dioxol-5-yl)acetic acid

Suppliers and Price of 1,3-Benzodioxole-5-acetic acid, 6-benzoyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,3-Benzodioxole-5-acetic acid, 6-benzoyl-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:284.06847348
Heavy Atom Count:21
Complexity:402

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C(=C2)CC(=O)O)C(=O)C3=CC=CC=C3

Technology Process of 1,3-Benzodioxole-5-acetic acid, 6-benzoyl-

There total 6 articles about 1,3-Benzodioxole-5-acetic acid, 6-benzoyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 53616-33-4
5-phenyl-1,3-dioxolo[4,5-g]isochromane

: 132813-86-6
2-Benzoyl-4,5-methylenedioxyphenylacetic acid

Guidance literature:: With chromium(VI) oxide; sulfuric acid; In acetone; at 15 - 20 ℃;
DOI:10.1021/jm0580003

Reference yield: 40.0%

: 132813-95-7
2-benzoyl-4,5-(methylenedioxy)-phenyl acetic acid methyl ester

: 132813-86-6
2-Benzoyl-4,5-methylenedioxyphenylacetic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 1h; Heating;

Reference yield:

: 2861-28-1
1,3-benzodioxole-5-acetic acid

: 132813-86-6
2-Benzoyl-4,5-methylenedioxyphenylacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 8 h / 20 °C

2: 75 percent / aq. HCl / toluene / 2 h / 20 °C

3: 81 percent / aq. H₂SO₄; CrO₃ / acetone / 15 - 20 °C

With chromium(VI) oxide; hydrogenchloride; lithium aluminium tetrahydride; sulfuric acid; In tetrahydrofuran; diethyl ether; acetone; toluene; 3: Jones oxidation;
DOI:10.1021/jm0580003