Propanediamide, N,N'-bis(2-aminophenyl)-

Base Information

• Chemical Name: Propanediamide, N,N'-bis(2-aminophenyl)-
• CAS No.: 132843-06-2
• Molecular Formula: C15H16N4O2
• Molecular Weight: 284.318
• DSSTox Substance ID: DTXSID30449362
• Nikkaji Number: J359.616H
• Wikidata: Q82268796
• Mol file: 132843-06-2.mol

Synonyms:Propanediamide, N,N'-bis(2-aminophenyl)-;132843-06-2;DTXSID30449362;N,N'-Bis(2-aminophenyl)malonamide

Chemical Property of Propanediamide, N,N'-bis(2-aminophenyl)-

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 284.12732577
• Heavy Atom Count: 21
• Complexity: 341

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N)NC(=O)CC(=O)NC2=CC=CC=C2N

Technology Process of Propanediamide, N,N'-bis(2-aminophenyl)-

There total 6 articles about Propanediamide, N,N'-bis(2-aminophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N,N'-bis-(2-nitro-phenyl)-malonamide (96331-35-0) → N,N'-Bis-(2-amino-phenyl)-malonamide (132843-06-2)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In water; ethyl acetate; at 20 ℃; for 4h;

DOI:10.1080/00958972.2019.1710138

Reference yield: 34.0%

carbon suboxide (504-64-3) + 1,2-diamino-benzene (95-54-5) → 1H-1,5-benzodiazepine-2,4(3H,5H)-dione (49799-48-6) + N,N'-Bis-(2-amino-phenyl)-malonamide (132843-06-2)

Guidance literature:

In chloroform; 1) 24h, 0 deg C, 2) 54h, r.t.;

Reference yield: 30.0%

N,N'-Bis-[2-(toluene-4-sulfonylamino)-phenyl]-malonamide (201297-17-8) → N,N'-Bis-(2-amino-phenyl)-malonamide (132843-06-2)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In acetonitrile; electrolysis, aluminum anode, carbon cathode, other reagent: tetramethylammonium bromide;

DOI:10.1016/S0040-4020(97)10095-3

upstream raw materials:

carbon suboxide

1,2-diamino-benzene

N,N'-Bis-[2-(toluene-4-sulfonylamino)-phenyl]-malonamide

N-tosyl-1,2-diaminobenzene

Refernces

• 1、 Lu. "Decisive role of Al3+ cation in the electrodetosylation of N, N'-bis- (o-tosylaminophenyl) propanediamide to N, N'-bis-(o-aminophenyl) propanediamide". . p. 16721 - 16730. Retrieved 2007/10/03.