[3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane

Base Information

Chemical Name:[3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane
CAS No.:133027-56-2
Molecular Formula:C17H29BrOSi
Molecular Weight:357.406
Hs Code.:
DSSTox Substance ID:DTXSID90565976
Wikidata:Q82451361

Synonyms:133027-56-2;SCHEMBL9009573;DTXSID90565976;[3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane

Suppliers and Price of [3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of [3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:7
Exact Mass:356.11710
Heavy Atom Count:20
Complexity:289

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C)(C)[Si](C)(C)OCCCC1=CC=CC=C1Br

Technology Process of [3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane

There total 5 articles about [3-(2-Bromophenyl)propoxy](2,3-dimethylbutan-2-yl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 52221-92-8
3-(2-bromo-phenyl)-propan-1-ol

: 67373-56-2
chlorodimethyl(1,1,2-trimethylpropyl)silane

: 133027-56-2
<3-(2-bromophenyl)propoxy>dimethyl(1,1,2-trimethylpropyl)silane

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 25 ℃; for 4h;
DOI:10.1021/jm00113a030

Reference yield:

: 6630-33-7
ortho-bromobenzaldehyde

: 133027-56-2
<3-(2-bromophenyl)propoxy>dimethyl(1,1,2-trimethylpropyl)silane

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / tetrahydrofuran / 18 h / 25 °C

2: 97 percent / H₂ / 5percent Rh/Al₂O₃ / methanol / 3 h

3: 100 percent / diisobutylaluminum hydride / toluene / 1.) -78 deg C, 2 h, 2.) from -78 deg C to 0 deg C, 2 h

4: 92 percent / 4-(dimethylamino)pyridine, triethylamine / CH₂Cl₂ / 4 h / 25 °C

With dmap; hydrogen; diisobutylaluminium hydride; triethylamine; Rh/Al₂O₃; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/jm00113a030

Reference yield:

: 102540-15-8,123100-53-8,92991-89-4
methyl (2E)-3-(2-bromophenyl)-2-propenoate

: 133027-56-2
<3-(2-bromophenyl)propoxy>dimethyl(1,1,2-trimethylpropyl)silane

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / H₂ / 5percent Rh/Al₂O₃ / methanol / 3 h

2: 100 percent / diisobutylaluminum hydride / toluene / 1.) -78 deg C, 2 h, 2.) from -78 deg C to 0 deg C, 2 h

3: 92 percent / 4-(dimethylamino)pyridine, triethylamine / CH₂Cl₂ / 4 h / 25 °C

With dmap; hydrogen; diisobutylaluminium hydride; triethylamine; Rh/Al₂O₃; In methanol; dichloromethane; toluene;
DOI:10.1021/jm00113a030