Technology Process of Bicyclo[5.3.1]undecan-11-one
There total 10 articles about Bicyclo[5.3.1]undecan-11-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: p-TsOH / methanol / 18 h / Heating
2: 1M lithium hydroxide / H2O; methanol; tetrahydrofuran / 25 °C
3: 1.) oxalyl chloride; 2.) sodium salt of 2-mercaptopyridine 1-oxide, dimethylaminopyridine / 1.) dimethylformamide, benzene, 25 degC, 1 h; 2.) tert-butyl thiol, toluene, reflux, 90 min
With
dmap; lithium hydroxide; oxalyl dichloride; 2-mercaptopyridine-1-oxide sodium salt; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; water;
DOI:10.1021/ja00280a071
- Guidance literature:
-
With
dmap; 2-mercaptopyridine-1-oxide sodium salt; 2-methylpropan-2-thiol;
In
toluene;
for 1.5h;
Yield given;
Heating;
DOI:10.1021/ja00023a037
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1M lithium hydroxide / H2O; methanol; tetrahydrofuran / 25 °C
2: 1.) oxalyl chloride; 2.) sodium salt of 2-mercaptopyridine 1-oxide, dimethylaminopyridine / 1.) dimethylformamide, benzene, 25 degC, 1 h; 2.) tert-butyl thiol, toluene, reflux, 90 min
With
dmap; lithium hydroxide; oxalyl dichloride; 2-mercaptopyridine-1-oxide sodium salt;
In
tetrahydrofuran; methanol; water;
DOI:10.1021/ja00280a071
