1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

Base Information

Chemical Name:1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-
CAS No.:133485-56-0
Molecular Formula:C15H17ClN2O
Molecular Weight:276.766
Hs Code.:
DSSTox Substance ID:DTXSID30435765
Wikidata:Q82250863

Synonyms:133485-56-0;1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-;SCHEMBL6960759;DTXSID30435765;VYLHMXUTTRBZEK-UHFFFAOYSA-N;2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde;2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazole-5-carboxaldehyde;2-n-butyl-1-[(2-chlorophenyl)methyl]-1H-imidazol-5-carboxaldehyde

Suppliers and Price of 1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:276.1029409
Heavy Atom Count:19
Complexity:287

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1=NC=C(N1CC2=CC=CC=C2Cl)C=O

Technology Process of 1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

There total 8 articles about 1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 133485-55-9
2-n-butyl-1-(2-chlorophenyl)-methyl-5-hydroxymethyl-1H-imidazole

: 133485-56-0
2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazole-5-carboxaldehyde

Guidance literature:: With manganese(IV) oxide; In dichloromethane; for 19h; Ambient temperature;
DOI:10.1021/jm00099a013

Reference yield:

: 17849-38-6
2-Chlorobenzyl alcohol

: 133485-56-0
2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazole-5-carboxaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: diisopropylethylamine / CH₂Cl₂ / 0.33 h / -78 °C

2: CH₂Cl₂ / 18 h / Ambient temperature

3: 10percent aq. NaOH / methanol / 4 h / Heating

4: 93 percent / MnO₂ / CH₂Cl₂ / 19 h / Ambient temperature

With manganese(IV) oxide; sodium hydroxide; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;
DOI:10.1021/jm00099a013

Reference yield:

: 133486-42-7
2-n-butyl-5-(acetoxymethyl)-1-<(2-chlorophenyl)methyl>imidazole

: 133485-56-0
2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazole-5-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 10percent aq. NaOH / methanol / 4 h / Heating

2: 93 percent / MnO₂ / CH₂Cl₂ / 19 h / Ambient temperature

With manganese(IV) oxide; sodium hydroxide; In methanol; dichloromethane;
DOI:10.1021/jm00099a013