N-(4-carbamimidoylphenyl)-Nalpha-[(4-methylphenyl)sulfonyl]phenylalaninamide

Base Information

Chemical Name:N-(4-carbamimidoylphenyl)-Nalpha-[(4-methylphenyl)sulfonyl]phenylalaninamide
CAS No.:92953-67-8
Molecular Formula:C₂₃H₂₄N₄O₃S
Molecular Weight:436.535
Hs Code.:

Synonyms:

Suppliers and Price of N-(4-carbamimidoylphenyl)-Nalpha-[(4-methylphenyl)sulfonyl]phenylalaninamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of N-(4-carbamimidoylphenyl)-Nalpha-[(4-methylphenyl)sulfonyl]phenylalaninamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.29g/cm³

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(4-carbamimidoylphenyl)-Nalpha-[(4-methylphenyl)sulfonyl]phenylalaninamide

There total 3 articles about N-(4-carbamimidoylphenyl)-Nalpha-[(4-methylphenyl)sulfonyl]phenylalaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₅NO₄SSi

: 2498-50-2,7761-72-0,15724-26-2
4-aminobenzamidine monohydrochloride

: 92953-67-8
N-(4-carbamimidoylphenyl)-3-phenyl-2-(p-tolylsulfonylamino)propanamide

Guidance literature:: With 1-methyl-pyrrolidin-2-one; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 100 ℃; for 0.166667h; Flow reactor;
DOI:10.1021/acs.jmedchem.7b01698

Reference yield:

: 150-30-1,25191-15-5,658-69-5,67675-33-6
Phenylalanine

: 92953-67-8
N-(4-carbamimidoylphenyl)-3-phenyl-2-(p-tolylsulfonylamino)propanamide

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / 100 °C / Microwave irradiation

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / 60 °C / Flow reactor

3: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; 1-methyl-pyrrolidin-2-one / dichloromethane / 0.17 h / 100 °C / Flow reactor

With 1-methyl-pyrrolidin-2-one; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane;
DOI:10.1021/acs.jmedchem.7b01698

Reference yield:

: 2899-42-5
DL-Phenylalanin-trimethylsilylester

: 92953-67-8
N-(4-carbamimidoylphenyl)-3-phenyl-2-(p-tolylsulfonylamino)propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / 60 °C / Flow reactor

2: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; 1-methyl-pyrrolidin-2-one / dichloromethane / 0.17 h / 100 °C / Flow reactor

With 1-methyl-pyrrolidin-2-one; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane;
DOI:10.1021/acs.jmedchem.7b01698