Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy-

Base Information

Chemical Name:Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy-
CAS No.:133568-82-8
Molecular Formula:C9H8ClN3O2
Molecular Weight:225.634
Hs Code.:
DSSTox Substance ID:DTXSID30439627
Wikidata:Q82255629

Synonyms:133568-82-8;Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy-;SCHEMBL9234654;DTXSID30439627

Suppliers and Price of Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy-

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:225.0305042
Heavy Atom Count:15
Complexity:288

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=C(C(=C1N)Cl)NC(=O)CO)C#N

Technology Process of Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy-

There total 2 articles about Acetamide, N-(3-amino-2-chloro-5-cyanophenyl)-2-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 133568-80-6
Acetic acid (3-amino-2-chloro-5-cyano-phenylcarbamoyl)-methyl ester

: 133568-82-8
N-(3-Amino-2-chloro-5-cyano-phenyl)-2-hydroxy-acetamide

Guidance literature:: With ammonium hydroxide; In methanol; for 1h; Ambient temperature;
DOI:10.1016/S0968-0896(98)00065-0

Reference yield:

: 34207-46-0
2-chloro-5-cyano-1,3-phenylenediamine

: 133568-82-8
N-(3-Amino-2-chloro-5-cyano-phenyl)-2-hydroxy-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / NaOH / diethyl ether / 0.25 h / Ambient temperature

2: 83 percent / aq. NH₃ / methanol / 1 h / Ambient temperature

With ammonium hydroxide; sodium hydroxide; In methanol; diethyl ether;
DOI:10.1016/S0968-0896(98)00065-0