Chemical Property of N-Desmethyl zolmitriptan
Chemical Property:
- Vapor Pressure:2.41E-13mmHg at 25°C
- Melting Point:63-66℃
- Boiling Point:577.7 °C at 760 mmHg
- PKA:12.57±0.40(Predicted)
- Flash Point:303.2 °C
- PSA：66.15000
- Density:1.235 g/cm3
- LogP:3.10240
- Storage Temp.:-20°C Freezer
- Solubility.:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- XLogP3:1.7
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:5
- Exact Mass:273.147726857
- Heavy Atom Count:20
- Complexity:350
- Purity/Quality:
-
97% *data from raw suppliers
N-DesmethylZolmitriptan *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CNCCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3
- Isomeric SMILES:CNCCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
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Description
N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan . DZT is an agonist of 5-HT1B receptors that induces contraction of isolated human cerebral arteries (EC50 = 100 nM).
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Uses
A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.
