Benzenepentanethioic acid, b-hydroxy-, S-ethyl ester, (R)-

Base Information

• Chemical Name: Benzenepentanethioic acid, b-hydroxy-, S-ethyl ester, (R)-
• CAS No.: 133910-29-9
• Molecular Formula: C13H18O2S
• Molecular Weight: 238.351
• Mol file: 133910-29-9.mol

Synonyms:

Chemical Property of Benzenepentanethioic acid, b-hydroxy-, S-ethyl ester, (R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepentanethioic acid, b-hydroxy-, S-ethyl ester, (R)-

There total 2 articles about Benzenepentanethioic acid, b-hydroxy-, S-ethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + 1-ethylthio-1-(trimethylsiloxy)ethene (63584-41-8) → S-ethyl 3-hydroxy-5-phenylpentanthioate (128806-21-3) + (S)-S-ethyl 3-hydroxy-5-phenylpentanethioate (133910-29-9)

Guidance literature:

With tin(II) trifluoromethanesulfonate; tributyltin fluoride; (2S)-1-methyl-2-<(N-1-naphthylamino)methyl>pyrrolidine; In dichloromethane; at -78 ℃; Yield given. Yields of byproduct given;

DOI:10.1021/ja00011a030

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + 1-ethylthio-1-(trimethylsiloxy)ethene (63584-41-8) → (S)-S-ethyl 3-hydroxy-5-phenylpentanethioate (133910-29-9)

Guidance literature:

With tin(II) trifluoromethanesulfonate; tributyltin fluoride; (S)-1-methyl-2-<(piperidin-1-yl)-methyl>pyrrolidine; In dichloromethane; at -78 ℃; for 12h; Yield given;

DOI:10.1246/cl.1989.297

upstream raw materials:

3-phenyl-propionaldehyde

1-ethylthio-1-(trimethylsiloxy)ethene