4-(Dibenzo[b,d]furan-3-yl)butanoic acid

Base Information

• Chemical Name: 4-(Dibenzo[b,d]furan-3-yl)butanoic acid
• CAS No.: 6948-74-9
• Molecular Formula: C16H14O3
• Molecular Weight: 254.2806
• NSC Number: 55909
• DSSTox Substance ID: DTXSID60288463
• Wikidata: Q82024877
• Mol file: 6948-74-9.mol

Synonyms:4-(dibenzo[b,d]furan-3-yl)butanoic acid;6948-74-9;3-Dibenzofuranbutyric acid;DTXSID60288463;NSC55909;NSC 55909;NSC-55909

Chemical Property of 4-(Dibenzo[b,d]furan-3-yl)butanoic acid

Chemical Property:

• Vapor Pressure: 8.44E-09mmHg at 25°C
• Boiling Point: 447.7°Cat760mmHg
• Flash Point: 224.6°C
• Density: 1.265g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 254.094294304
• Heavy Atom Count: 19
• Complexity: 328

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)CCCC(=O)O

Technology Process of 4-(Dibenzo[b,d]furan-3-yl)butanoic acid

There total 4 articles about 4-(Dibenzo[b,d]furan-3-yl)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-dibenzofuran-3-yl-4-oxo-butyric acid (52852-49-0) → 4-dibenzofuran-3-yl-butyric acid (6948-74-9)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; diethylene glycol; at 200 ℃;

Reference yield:

dibenzo[b,d]furan-3-carbonitrile (29021-90-7) → 4-dibenzofuran-3-yl-butyric acid (6948-74-9)

Guidance literature:

Multi-step reaction with 4 steps

1: diethyl ether / anschliessend behandeln mit wss. Salzsaeure

2: bromine; chloroform

3: benzene / Erwaermen des Reaktionsprodukts mit methanol. Kalilauge und Erhitzen der erhaltenen Dicarbonsaeure auf 200grad

4: hydrazine hydrate; potassium hydroxide; diethylene glycol / 200 °C

With potassium hydroxide; diethyl ether; chloroform; bromine; hydrazine hydrate; diethylene glycol; benzene;

Reference yield:

3-acetyl-dibenzofuran (29640-76-4) → 4-dibenzofuran-3-yl-butyric acid (6948-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: bromine; chloroform

2: benzene / Erwaermen des Reaktionsprodukts mit methanol. Kalilauge und Erhitzen der erhaltenen Dicarbonsaeure auf 200grad

3: hydrazine hydrate; potassium hydroxide; diethylene glycol / 200 °C

With potassium hydroxide; chloroform; bromine; hydrazine hydrate; diethylene glycol; benzene;

upstream raw materials:

4-dibenzofuran-3-yl-4-oxo-butyric acid

dibenzo[b,d]furan-3-carbonitrile

3-acetyl-dibenzofuran

3-(bromoacetyl)dibenzofuran