(3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Base Information

Chemical Name:(3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CAS No.:134732-98-2
Molecular Formula:C10H12N2O
Molecular Weight:176.21500
Hs Code.:
Mol file:134732-98-2.mol

Synonyms:1,2,3,4-tetrahydrodibenzothiophen-1-one oxime;1,2,3,4-tetrahydroisoquinolin-7-ylboronic acid;

Suppliers and Price of (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
100mg
$ 200.00

J&W Pharmlab
(S)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylicacidamide 96%
100mg
$ 212.00

Crysdot
(S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxamide 95+%
1g
$ 374.00

Chemenu
(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide 95%
1g
$ 354.00

American Custom Chemicals Corporation
(3S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE 95.00%
2.5G
$ 1011.60

American Custom Chemicals Corporation
(3S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE 95.00%
1G
$ 656.25

AccelPharmtech
(3S)-1,2,3,4-tetrahydro-3-Isoquinolinecarboxamide 97.00%
5G
$ 2750.00

AccelPharmtech
(3S)-1,2,3,4-tetrahydro-3-Isoquinolinecarboxamide 97.00%
1G
$ 2370.00

Total 11 raw suppliers

Chemical Property of (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Chemical Property:

PSA：56.11000
LogP:1.66470

Purity/Quality:

97% ^*data from raw suppliers

(3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (3S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxamide is an organocatalyst for asymmetric aldol reaction.

Technology Process of (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

There total 8 articles about (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 150417-15-5
(S)-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

: 134732-98-2
(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 12h;
DOI:10.1016/j.tetlet.2004.07.112

Reference yield: 82.0%

: 79815-19-3,79799-05-6
methyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate

: 134732-98-2
(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 24h;

Reference yield:

: 115962-35-1,144069-68-1,78879-20-6
(3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid

: 134732-98-2
(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: NH₃; EDC; HOBt / DIEA / dioxane; dimethylformamide

2: TFA / CH₂Cl₂

With ammonia; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.11.103