1-Phenylethyl diphenylphosphinite

Base Information

• Chemical Name: 1-Phenylethyl diphenylphosphinite
• CAS No.: 134920-71-1
• Molecular Formula: C20H19OP
• Molecular Weight: 306.344
• DSSTox Substance ID: DTXSID90565138
• Nikkaji Number: J1.915.320G
• Mol file: 134920-71-1.mol

Synonyms:134920-71-1;1-Phenylethyl diphenylphosphinite;diphenyl(1-phenylethoxy)phosphane;DTXSID90565138

Chemical Property of 1-Phenylethyl diphenylphosphinite

Chemical Property:

• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 306.117352223
• Heavy Atom Count: 22
• Complexity: 283

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)OP(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-Phenylethyl diphenylphosphinite

There total 3 articles about 1-Phenylethyl diphenylphosphinite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-Phenylethanol (98-85-1,13323-81-4) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1-Diphenylphosphinoxy-1-phenylethan (134920-71-1)

Guidance literature:

With dmap; triethylamine; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1246/cl.2005.1124

Reference yield:

1-Phenylethanol (98-85-1,13323-81-4) + (dimethylamino)(diphenyl)phosphine (6840-01-3) → 1-Diphenylphosphinoxy-1-phenylethan (134920-71-1)

Guidance literature:

In 1,2-dichloro-ethane; at 100 ℃; for 7h;

DOI:10.1246/bcsj.76.1645

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1-Diphenylphosphinoxy-1-phenylethan (134920-71-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / benzene / 0 - 20 °C

2: 1,2-dichloro-ethane / 7 h / 100 °C

In 1,2-dichloro-ethane; benzene;

DOI:10.1246/bcsj.76.1645

upstream raw materials:

1-Phenylethanol

chloro-diphenylphosphine

(dimethylamino)(diphenyl)phosphine

Downstream raw materials:

(α-methylbenzyl)diphenylphosphine oxide

Diphenylphosphine oxide

α-phenoxyethylbenzene

1-phenylethyl isocyanide