2-Ethoxymethyl-5-hydroxy-gamma-pyrone

Base Information

Chemical Name:2-Ethoxymethyl-5-hydroxy-gamma-pyrone
CAS No.:135100-43-5
Molecular Formula:C₈H₁₀O₄
Molecular Weight:170.165
Hs Code.:
DSSTox Substance ID:DTXSID30879160
Nikkaji Number:J771.803I
Wikidata:Q82861214
ChEMBL ID:CHEMBL120412
Mol file:135100-43-5.mol

Synonyms:CHEMBL120412;135100-43-5;2-ethoxymethyl-5-hydroxy-gamma-pyrone;SCHEMBL3258342;DTXSID30879160;GCMPGTUGHASJNO-UHFFFAOYSA-N;BDBM50436138;4H-Pyran-4-one, 2-EtOMe-5-hydroxy-;2-(Ethoxymethyl)-5-hydroxy-4H-pyran-4-one

Suppliers and Price of 2-Ethoxymethyl-5-hydroxy-gamma-pyrone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Ethoxymethyl-5-hydroxy-gamma-pyrone

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:170.05790880
Heavy Atom Count:12
Complexity:239

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOCC1=CC(=O)C(=CO1)O

Technology Process of 2-Ethoxymethyl-5-hydroxy-gamma-pyrone

There total 5 articles about 2-Ethoxymethyl-5-hydroxy-gamma-pyrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 181431-42-5
5-Benzyloxy-2-ethoxymethyl-pyran-4-one

: 135100-43-5
2-(ethoxymethyl)-5-hydroxy-4H-pyran-4-one

Guidance literature:: With hydrogenchloride; for 2h; Heating;
DOI:10.1021/jm960220g

Reference yield:

: 1443302-08-6
2-(ethoxymethyl)-5-(4-methoxybenzyloxy)-4H-pyran-4-one

: 135100-43-5
2-(ethoxymethyl)-5-hydroxy-4H-pyran-4-one

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1016/j.bmcl.2013.04.062

Reference yield:

: 15771-06-9
5-benzyloxy-2-hydroxymethyl-4H-pyran-4-one

: 135100-43-5
2-(ethoxymethyl)-5-hydroxy-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 1 h / 20 °C

2: aq. HCl / 0.5 h / Heating

With hydrogenchloride; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.03.087