Benzenepropanoic acid, 3-chloro-b-hydroxy-, methyl ester, (R)-

Base Information

Chemical Name:Benzenepropanoic acid, 3-chloro-b-hydroxy-, methyl ester, (R)-
CAS No.:135505-20-3
Molecular Formula:C10H11ClO3
Molecular Weight:214.649
Hs Code.:
Mol file:135505-20-3.mol

Synonyms:methyl (S)-3-(3'-chlorophenyl)-3-hydroxypropionate;(3S)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate;(S)-3-(3-Chloro-phenyl)-3-hydroxy-propionic acid methyl ester;(S)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate;Methyl (S)-3-(3-Chlorophenyl)-3-hydroxypropanoate;

Suppliers and Price of Benzenepropanoic acid, 3-chloro-b-hydroxy-, methyl ester, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Benzenepropanoic acid, 3-chloro-b-hydroxy-, methyl ester, (R)-

Chemical Property:

PSA：46.53000
LogP:1.93650

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzenepropanoic acid, 3-chloro-b-hydroxy-, methyl ester, (R)-

There total 15 articles about Benzenepropanoic acid, 3-chloro-b-hydroxy-, methyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 632327-19-6
methyl 3-(3-chlorophenyl)-3-oxopropanoate

: 135505-20-3
(S)-(-)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate

Guidance literature:: With formic acid; triethylamine; at 0 - 45 ℃; for 2.83333h;

methyl 3-(3-chlorophenyl)-3-oxopropanoate; [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); In DMF (N,N-dimethyl-formamide); at 20 - 60 ℃; for 12.25h;

Reference yield:

: 632327-19-6
methyl 3-(3-chlorophenyl)-3-oxopropanoate

: 135505-20-3
(R)-(+)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate

: 135505-20-3
(S)-(-)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; C₃₇H₃₅FeN₂P; potassium tert-butylate; hydrogen; In methanol; at 20 ℃; for 12h; under 15001.5 Torr; Overall yield = 95 %; enantioselective reaction; Autoclave; Glovebox;
DOI:10.1039/c7ra00472a

Reference yield:

: 632327-19-6
methyl 3-(3-chlorophenyl)-3-oxopropanoate

: 135505-20-3
(R)-(+)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate

: 135505-20-3
(S)-(-)-methyl 3-(3-chlorophenyl)-3-hydroxypropanoate

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; C₃₇H₃₅FeN₂P; potassium tert-butylate; hydrogen; In methanol; at 20 ℃; for 12h; under 15001.5 Torr; Overall yield = 95 %; enantioselective reaction; Autoclave; Glovebox;
DOI:10.1039/c7ra00472a