benzo[d][1,2,3]thiadiazol-4-aMine

Base Information

• Chemical Name: benzo[d][1,2,3]thiadiazol-4-aMine
• CAS No.: 13599-80-9
• Molecular Formula: C6H5N3S
• Molecular Weight: 151.18900
• Mol file: 13599-80-9.mol

Synonyms:4-amino-1,2,3-benzothiadiazole;1,2,3-benzothiadiazol-4-amine;4-Amino-benzothiadiazol;Benzo[1,2,3]thiadiazol-4-ylamine;4-aminobenzothiadiazole;Benzo[1,2,3]thiadiazol-4-ylamin;4-Amino-1.2.3-benzothiadiazol;

Chemical Property of benzo[d][1,2,3]thiadiazol-4-aMine

Chemical Property:

• PSA: 80.04000
• LogP: 1.85470

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzo[d][1,2,3]thiadiazol-4-aMine

There total 5 articles about benzo[d][1,2,3]thiadiazol-4-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

benzo[1,2,3]thiadiazole (273-77-8) → 1,2,3-benzothiadiazol-5-amine (1753-29-3) + benzo[d][1,2,3]thiadiazol-7-amine (1753-30-6) + 4-Amino-1.2.3-benzothiadiazol (13599-80-9)

Guidance literature:

benzo[1,2,3]thiadiazole; With sulfuric acid; potassium nitrate; at 10 - 20 ℃; for 16.5h;

With hydrogenchloride; iron; In ethanol; water; for 1h; Reflux;

Reference yield:

2-amino-benzenethiol (137-07-5) → 1,2,3-benzothiadiazol-5-amine (1753-29-3) + 4-Amino-1.2.3-benzothiadiazol (13599-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenchloride; sodium nitrite / water; tetrahydrofuran / 0.5 h / 20 °C

2.1: potassium nitrate; sulfuric acid / 16.5 h / 10 - 20 °C

2.2: 1 h / Reflux

With hydrogenchloride; sulfuric acid; potassium nitrate; sodium nitrite; In tetrahydrofuran; water;

Reference yield:

4-nitro-benzo[1,2,3]thiadiazole (13599-79-6) → 4-Amino-1.2.3-benzothiadiazol (13599-80-9)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

DOI:10.1039/jr9620002374

upstream raw materials:

4-nitro-benzo[1,2,3]thiadiazole

2-amino-benzenethiol

benzo[1,2,3]thiadiazole

Downstream raw materials:

7-phenylazo-benzo[1,2,3]thiadiazol-4-ylamine

7-(4-chloro-phenylazo)-benzo[1,2,3]thiadiazol-4-ylamine

N-benzo[1,2,3]thiadiazol-4-yl-toluene-4-sulfonamide

4-acetylamino-N-benzo[1,2,3]thiadiazol-4-yl-benzenesulfonamide