Para-Tolyl 4-Aminosalicylate

Base Information

• Chemical Name: Para-Tolyl 4-Aminosalicylate
• CAS No.: 56356-15-1
• Molecular Formula: C14H13NO3
• Molecular Weight: 243.2579
• Hs Code.: 2922509090
• European Community (EC) Number: 654-963-2
• NSC Number: 96639
• DSSTox Substance ID: DTXSID50204910
• Nikkaji Number: J1.576.363I
• Wikidata: Q83078387
• ChEMBL ID: CHEMBL1413772
• Mol file: 56356-15-1.mol

Synonyms:Para-Tolyl 4-Aminosalicylate;56356-15-1;Salicylic acid, 4-amino-, p-tolyl ester;p-Tolyl pas;p-Tolyl-4-aminosalicylate;4-Aminosalicylic acid p-tolyl ester;BRN 2855293;(4-methylphenyl) 4-amino-2-hydroxybenzoate;Benzoic acid, 4-amino-2-hydroxy-, 4-methylphenyl ester;4-14-00-01981 (Beilstein Handbook Reference);cid_91815;CHEMBL1413772;BDBM32218;DTXSID50204910;p-Tolyl 4-amino-2-hydroxybenzoate;NSC96639;p-tolyl 4-amino-2-hydroxy-benzoate;NSC 96639;NSC-96639;AKOS024332780;4-amino-2-hydroxy-benzoic acid p-tolyl ester;(4-methylphenyl) 4-azanyl-2-oxidanyl-benzoate;4-amino-2-hydroxybenzoic acid (4-methylphenyl) ester

Chemical Property of Para-Tolyl 4-Aminosalicylate

Chemical Property:

• Vapor Pressure: 4.65E-07mmHg at 25°C
• Boiling Point: 402.6°Cat760mmHg
• Flash Point: 197.3°C
• PSA: 72.55000
• Density: 1.281g/cm³
• LogP: 3.08320
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 243.08954328
• Heavy Atom Count: 18
• Complexity: 287

Purity/Quality:

97% ^*data from raw suppliers

PARA-TOLYL 4-AMINOSALICYLATE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)OC(=O)C2=C(C=C(C=C2)N)O

Technology Process of Para-Tolyl 4-Aminosalicylate

There total 2 articles about Para-Tolyl 4-Aminosalicylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-4-nitro-benzoic acid p-tolyl ester → 4-amino-2-hydroxy-benzoic acid p-tolyl ester (56356-15-1)

Guidance literature:

With ethyl acetate; platinum; Hydrogenation;

Reference yield:

p-cresol (106-44-5) + 4-Aminosalicylic acid (65-49-6) → 4-amino-2-hydroxy-benzoic acid p-tolyl ester (56356-15-1)

Guidance literature:

With thionyl chloride; N,N-dimethyl-aniline; benzene;

upstream raw materials:

p-cresol

4-Aminosalicylic acid