Technology Process of Benzenepropanal, b-ethenyl-, (S)-
There total 9 articles about Benzenepropanal, b-ethenyl-, (S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
periodic acid;
In
tetrahydrofuran; diethyl ether;
at 0 ℃;
for 1h;
DOI:10.1002/anie.202110709
- Guidance literature:
-
With
(R)-aluminum tris(1-naphthyl-3-(p-fluorophenyl)-2-napthoxide);
In
toluene;
at -78 ℃;
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/ja00108a048
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: titanium(IV) isopropylate / tetrahydrofuran / 12.5 h / 0 - 20 °C / Inert atmosphere
2.1: C43H35N2O3(1+)*BF4(1-); tetrakis(actonitrile)copper(I) hexafluorophosphate; lithium tert-butoxide / tetrahydrofuran / 24 h / -20 °C / Schlenk technique; Inert atmosphere
3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.17 h / -78 °C / Schlenk technique; Inert atmosphere
3.2: 2 h / -78 - 0 °C / Schlenk technique; Inert atmosphere
4.1: 3-chloro-benzenecarboperoxoic acid; sodium acetate / dichloromethane / 3 h / 0 °C
5.1: periodic acid / tetrahydrofuran; diethyl ether / 1 h / 0 °C
With
titanium(IV) isopropylate; tetrakis(actonitrile)copper(I) hexafluorophosphate; sodium acetate; C43H35N2O3(1+)*BF4(1-); periodic acid; 3-chloro-benzenecarboperoxoic acid; lithium tert-butoxide; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1002/anie.202110709
