(4-benzylpiperazino)(1H-indol-3-yl)methanone

Base Information

Chemical Name:(4-benzylpiperazino)(1H-indol-3-yl)methanone
CAS No.:137643-31-3
Molecular Formula:C20H21N3O
Molecular Weight:319.40000
Hs Code.:
DSSTox Substance ID:DTXSID50402237
Nikkaji Number:J3.204.199J
Wikidata:Q82205615
ChEMBL ID:CHEMBL318990
Mol file:137643-31-3.mol

Synonyms:(4-benzylpiperazino)(1H-indol-3-yl)methanone;137643-31-3;(4-benzylpiperazin-1-yl)-(1H-indol-3-yl)methanone;CHEMBL318990;MLS000763325;SCHEMBL8301611;DTXSID50402237;BDBM50132382;MFCD03305788;AKOS005100008;SMR000336191;(1H-Indole-3-yl)(4-benzylpiperazino) ketone;3-(4-benzylpiperazine-1-carbonyl)-1H-indole;7T-1490;(4-Benzyl-piperazin-1-yl)-(1H-indol-3-yl)-methanone

Suppliers and Price of (4-benzylpiperazino)(1H-indol-3-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(4-BENZYLPIPERAZINO)(1H-INDOL-3-YL)METHANONE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
(4-BENZYLPIPERAZINO)(1H-INDOL-3-YL)METHANONE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
(4-BENZYLPIPERAZINO)(1H-INDOL-3-YL)METHANONE 95.00%
1MG
$ 647.61

Total 1 raw suppliers

Chemical Property of (4-benzylpiperazino)(1H-indol-3-yl)methanone

Chemical Property:

PSA：39.34000
LogP:3.00170
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:319.168462302
Heavy Atom Count:24
Complexity:427

Purity/Quality:

99.90% ^*data from raw suppliers

(4-BENZYLPIPERAZINO)(1H-INDOL-3-YL)METHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)C(=O)C3=CNC4=CC=CC=C43

Technology Process of (4-benzylpiperazino)(1H-indol-3-yl)methanone

There total 3 articles about (4-benzylpiperazino)(1H-indol-3-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 120-72-9
indole

: 1392831-25-2
(4-benzylpiperazin-1-yl)(imidazol-1-yl)methanone

: 137643-31-3
(1H-indol-3-yl)[4′-(phenylmethyl)piperazin-1′-yl]methanone

Guidance literature:: With trimethylaluminum; In toluene; at 110 ℃; for 48h; regioselective reaction;
DOI:10.1002/ejoc.201300085

Reference yield: 50.0%

: 120-72-9
indole

: 2759-28-6
1-phenylmethylpiperazine

: 67-66-3,8013-54-5
chloroform

: 137643-31-3
(1H-indol-3-yl)[4′-(phenylmethyl)piperazin-1′-yl]methanone

Guidance literature:: With dimethyl zinc(II); In hexane; at 20 ℃; for 48h;
DOI:10.1002/ejoc.201800571

Reference yield:

: 771-50-6
1H-indole-3-carboxylic acid

: 2759-28-6
1-phenylmethylpiperazine

: 137643-31-3
(1H-indol-3-yl)[4′-(phenylmethyl)piperazin-1′-yl]methanone

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/S0960-894X(03)00653-X