Technology Process of Methyl 6-(3-aminobutyl)-2,3-dichlorobenzoate
There total 5 articles about Methyl 6-(3-aminobutyl)-2,3-dichlorobenzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
ammonium acetate; 4 A molecular sieve; sodium cyanoborohydride;
In
methanol;
for 72h;
Ambient temperature;
DOI:10.1002/jhet.5570280622
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 79 percent / NaH / 1,2-dimethoxy-ethane / 18 h / Ambient temperature
2: 79 percent / NaBH4 / propan-2-ol / 48 h / Heating
3: diethyl ether / 36 h / Ambient temperature
4: 1.) NaH / 1.) dimethylformamide, 0 deg C, 20 min, 2.) overnight
5: 62 percent / ammonium acetate, sodium cyanoborohydride, 4 Angstroem molecular sieves / methanol / 72 h / Ambient temperature
With
ammonium acetate; sodium tetrahydroborate; 4 A molecular sieve; sodium hydride; sodium cyanoborohydride;
In
methanol; 1,2-dimethoxyethane; diethyl ether; isopropyl alcohol;
DOI:10.1002/jhet.5570280622
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 79 percent / NaBH4 / propan-2-ol / 48 h / Heating
2: diethyl ether / 36 h / Ambient temperature
3: 1.) NaH / 1.) dimethylformamide, 0 deg C, 20 min, 2.) overnight
4: 62 percent / ammonium acetate, sodium cyanoborohydride, 4 Angstroem molecular sieves / methanol / 72 h / Ambient temperature
With
ammonium acetate; sodium tetrahydroborate; 4 A molecular sieve; sodium hydride; sodium cyanoborohydride;
In
methanol; diethyl ether; isopropyl alcohol;
DOI:10.1002/jhet.5570280622
