1,2-dibromocyclopentane

Base Information

• Chemical Name: 1,2-dibromocyclopentane
• CAS No.: 10230-26-9
• Molecular Formula: C5H8 Br2
• Molecular Weight: 227.927
• Hs Code.: 2903890090
• Mol file: 10230-26-9.mol

Synonyms:Cyclopentane,1,2-dibromo-, trans- (8CI); trans-1,2-Dibromocyclopentane

Chemical Property of 1,2-dibromocyclopentane

Chemical Property:

• Vapor Pressure: 0.548mmHg at 25°C
• Refractive Index: n20/D 1.550
• Boiling Point: 196.9°Cat760mmHg
• Flash Point: 71.5°C
• PSA: 0.00000
• Density: 1.94g/cm³
• LogP: 2.69730

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-1,2-Dibromocyclopentane 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-dibromocyclopentane

There total 26 articles about 1,2-dibromocyclopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

cyclopentene (142-29-0) → trans-1,2-dibromocyclopentane (10230-26-9)

Guidance literature:

With Oxalyl bromide; dimethyl sulfoxide; In dichloromethane; at -10 - 20 ℃; for 0.5h; stereoselective reaction; Inert atmosphere;

DOI:10.1055/s-0037-1609560

Reference yield: 90.18%

Cyclopentane (287-92-3) → trans-1,2-dibromocyclopentane (10230-26-9)

Guidance literature:

With bromine; In dichloromethane; at -5 - 10 ℃;

Reference yield: 87.0%

cyclopentene (142-29-0) → trans-1,2-dibromocyclopentane (10230-26-9) + cyclopentanone (120-92-3)

Guidance literature:

With water; oxygen; lithium bromide; copper(ll) bromide; In tetrahydrofuran; at 25 ℃; under 760.051 Torr;

upstream raw materials:

cyclopentene

Cyclopentyl bromide

Cyclopentane

1-bromocyclopentene

Downstream raw materials:

trans-1,2-dimethoxycyclopentane

cis-1,2-cyclopentanediol

trans-cyclopentane-1,2-diol

1,2-trans-diaminocyclopentane diiodoplatinum(II)

Refernces

• 1、 Ryu, Ilhyong,Matsubara, Hiroshi,Yasuda, Shinji,Nakamura, Hiroyuki,Curran, Dennis P.. "Phase-vanishing reactions that use fluorous media as a phase screen. Facile, controlled bromination of alkenes by dibromine and dealkylation of aromatic ethers by boron tribromide". . p. 12946 - 12947. Retrieved 2002.
• 2、 Ding, Rui,Li, Jiaqi,Jiao, Wenyi,Han, Mengru,Liu, Yongguo,Tian, Hongyu,Sun, Baoguo. "A Highly Efficient Method for the Bromination of Alkenes, Alkynes and Ketones Using Dimethyl Sulfoxide and Oxalyl Bromide". . p. 4325 - 4335. Retrieved 2018/11/21.
• 3、 -. "A method for the treatment of tumor cell proliferative diseases of platinum (II) compound". Paragraph 0249; 0256; 0257; 0258; 0259. . Retrieved 2018/01/11.