[(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid

Base Information

Chemical Name:[(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid
CAS No.:1746-32-3
Molecular Formula:C₈H₁₆NO₉P
Molecular Weight:301.19
Hs Code.:
DSSTox Substance ID:DTXSID60938532
Nikkaji Number:J1.734.828K
Wikidata:Q82914860
Mol file:1746-32-3.mol

Synonyms:GlcNAc6P;N-acetylglucosamine 6-phosphate

Suppliers and Price of [(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of [(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:1.83±0.10(Predicted)
Flash Point:°C
PSA：183.43000
Density:1.642g/cm³
LogP:-2.72710
XLogP3:-4.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:301.05626809
Heavy Atom Count:19
Complexity:356

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(C=O)C(C(C(COP(=O)(O)O)O)O)O
Isomeric SMILES:CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O

Technology Process of [(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid

There total 6 articles about [(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100663-39-6
O¹,O³,O⁴-triacetyl-2-acetylamino-O⁶-phosphono-2-deoxy-β-D-glucopyranose

: 1746-32-3
2-N-acetylamino-2-deoxy-D-glucose-6-phosphate

Guidance literature:: With ammonia;
DOI:10.1021/ja01588a034

Reference yield:

: 35946-64-6
2-deoxy-2-(4-methoxybenzylidene)amino-D-glucose

: 1746-32-3
2-N-acetylamino-2-deoxy-D-glucose-6-phosphate

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine; acetic acid anhydride

2: acetone; aqueous hydrochloric acid

3: acetic acid anhydride; pyridine

4: platinum; acetic acid / Hydrogenation

5: methanol.ammonia

With pyridine; hydrogenchloride; ammonia; acetic anhydride; acetic acid; acetone; platinum;
DOI:10.1021/ja01588a034

Reference yield:

: 71525-74-1
O¹,O³,O⁴-triacetyl-2-amino-O⁶-diphenoxyphosphoryl-2-deoxy-β-D-glucopyranose

: 1746-32-3
2-N-acetylamino-2-deoxy-D-glucose-6-phosphate

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid anhydride; pyridine

2: platinum; acetic acid / Hydrogenation

3: methanol.ammonia

With pyridine; ammonia; acetic anhydride; acetic acid; platinum;
DOI:10.1021/ja01588a034