Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate

Base Information

Chemical Name:Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate
CAS No.:137964-82-0
Molecular Formula:C12H15N3O4
Molecular Weight:265.269
Hs Code.:
DSSTox Substance ID:DTXSID80568335
Wikidata:Q82454560
Mol file:137964-82-0.mol

Synonyms:137964-82-0;Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate;DTXSID80568335

Suppliers and Price of Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:265.10625597
Heavy Atom Count:19
Complexity:344

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C=C(C=C1OCOC)C)N=[N+]=[N-]

Technology Process of Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate

There total 3 articles about Ethyl 2-azido-6-(methoxymethoxy)-4-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 137964-81-9
2-Benzylamino-6-hydroxy-4-methyl-benzoic acid ethyl ester

: 137964-82-0
2-Azido-6-methoxymethoxy-4-methyl-benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Pd/C / ethanol / 2 h / 23 °C / 62057.8 Torr

2: 1.) aq. NaNO₂, HCl, 2.) NaN₃ / 1.) EtOH, 0 deg C, 20 min, 2.) EtOH, 0 deg C, 40 min

3: i-Pr₂NEt / CH₂Cl₂ / 23 °C

With hydrogenchloride; sodium azide; hydrogen; N-ethyl-N,N-diisopropylamine; sodium nitrite; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/ja00027a071

Reference yield:

: 2-Azido-6-hydroxy-4-methyl-benzoic acid ethyl ester

: 107-30-2
chloromethyl methyl ether

: 137964-82-0
2-Azido-6-methoxymethoxy-4-methyl-benzoic acid ethyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 23 ℃; Yield given;
DOI:10.1021/ja00027a071

Reference yield:

: 2-Amino-6-hydroxy-4-methyl-benzoic acid ethyl ester

: 137964-82-0
2-Azido-6-methoxymethoxy-4-methyl-benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaNO₂, HCl, 2.) NaN₃ / 1.) EtOH, 0 deg C, 20 min, 2.) EtOH, 0 deg C, 40 min

2: i-Pr₂NEt / CH₂Cl₂ / 23 °C

With hydrogenchloride; sodium azide; N-ethyl-N,N-diisopropylamine; sodium nitrite; In dichloromethane;
DOI:10.1021/ja00027a071