Ppahv

Base Information

Chemical Name:Ppahv
CAS No.:175796-50-6
Molecular Formula:C39H44 O11
Molecular Weight:688.772
Hs Code.:
DSSTox Substance ID:DTXSID10938709
Nikkaji Number:J738.482C
Wikidata:Q27088432
Pharos Ligand ID:7GWL9UK622AB
ChEMBL ID:CHEMBL104647
Mol file:175796-50-6.mol

Synonyms:phorbol 12-phenylacetate 13-acetate 20-homovanillate;PPAHV

Suppliers and Price of Ppahv

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
PPAHV
1mg
$ 403.00

TRC
PPAHV
2.5mg
$ 90.00

Sigma-Aldrich
Phorbol 12-phenylacetate 13-acetate 20-homovanillate solid
.5mg
$ 163.00

ApexBio Technology
PPAHV
1mg
$ 228.00

American Custom Chemicals Corporation
PHORBOL 12-PHENYLACETATE 13-ACETATE 20-HOMOVANILLATE 95.00%
1MG
$ 642.99

Total 4 raw suppliers

Chemical Property of Ppahv

Chemical Property:

Vapor Pressure:1.8E-26mmHg at 25°C
Boiling Point:792.4°Cat760mmHg
Flash Point:241.1°C
PSA：165.89000
Density:1.36g/cm³
LogP:3.80230
Storage Temp.:Desiccate at -20°C
Solubility.:DMSO: soluble
XLogP3:3.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:12
Exact Mass:688.28836222
Heavy Atom Count:50
Complexity:1440

Purity/Quality:

≥98% by HPLC ^*data from raw suppliers

PPAHV ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C2(C(C2(C)C)C3C1(C4C=C(C(=O)C4(CC(=C3)COC(=O)CC5=CC(=C(C=C5)O)OC)O)C)O)OC(=O)C)OC(=O)CC6=CC=CC=C6
Isomeric SMILES:C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)COC(=O)CC5=CC(=C(C=C5)O)OC)O)C)O)OC(=O)C)OC(=O)CC6=CC=CC=C6
Uses PPAHV is non-pungent resiniferatoxin-type phorboid vanilloid and agonist.

Technology Process of Ppahv

There total 11 articles about Ppahv which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 179258-46-9
phorbol 12-phenylacetate 13-acetate 20-(MEM-homovanillate)

: 175796-50-6
PPAHV

Guidance literature:: With tin(IV) chloride; In tetrahydrofuran; for 1.5h;
DOI:10.1021/jm960063l

Reference yield:

: 82400-03-1
phorbol-20-trityl ether

: 175796-50-6
PPAHV

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / tetrahydrofuran

2: dicyclohexylcarbodiimide / dimethylaminopyridine

3: HClO₄

4: dicyclohexylcarbodiimide / dimethylaminopyridine

5: SnCl₄ / tetrahydrofuran

With tin(IV) chloride; dicyclohexyl-carbodiimide; dmap; perchloric acid; triethylamine; In tetrahydrofuran; 1: Acetylation / 2: Esterification / 3: detritylation / 4: Esterification / 5: phenolic MEM-ether cleavage;
DOI:10.1016/0014-2999(95)00864-0

Reference yield:

: 179258-26-5
phorbol 12-phenylacetate 13-acetate

: 175796-50-6
PPAHV

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexylcarbodiimide / dimethylaminopyridine

2: SnCl₄ / tetrahydrofuran

With tin(IV) chloride; dicyclohexyl-carbodiimide; dmap; In tetrahydrofuran; 1: Esterification / 2: phenolic MEM-ether cleavage;
DOI:10.1016/0014-2999(95)00864-0