Chemical Property of Dimethindene maleate
Chemical Property:
- Vapor Pressure:3.85E-07mmHg at 25°C
- Melting Point:159-161℃
- Boiling Point:416.3°Cat760mmHg
- Flash Point:205.6°C
- PSA:90.73000
- Density:g/cm3
- LogP:3.85850
- Storage Temp.:-20°C Freezer, Under inert atmosphere
- Solubility.:Slightly soluble in water, soluble in methanol
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:7
- Exact Mass:408.20490738
- Heavy Atom Count:30
- Complexity:518
- Purity/Quality:
-
99%, *data from raw suppliers
DimethindeneMaleate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
- Canonical SMILES:CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C.C(=CC(=O)O)C(=O)O
- Isomeric SMILES:CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C.C(=C\C(=O)O)\C(=O)O
- Recent EU Clinical Trials:A phase IIa, single-center, randomized, reference-controlled, observer-blind trial to assess the efficacy of a topical Aescin formulation in experimentally induced itch, wheal and flare reactions in patients with type-I allergy
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Uses
Dimethindene Maleate is a salt of Dimethindene which is an antihistamine/anticholinergic used orally and locally as an antipruritic. Dimethindene is an H1-antagonist of high potency. Antihistaminic.
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Therapeutic Function
Antihistaminic