4-(Cbz-amino)tetrahydropyran-4-carboxylic acid

Base Information

Chemical Name:4-(Cbz-amino)tetrahydropyran-4-carboxylic acid
CAS No.:138402-13-8
Molecular Formula:C14H17NO5
Molecular Weight:279.293
Hs Code.:2932990090
DSSTox Substance ID:DTXSID40598693
Wikidata:Q82494482
Mol file:138402-13-8.mol

Synonyms:138402-13-8;4-(CBZ-AMINO)TETRAHYDROPYRAN-4-CARBOXYLIC ACID;4-(phenylmethoxycarbonylamino)oxane-4-carboxylic acid;4-{[(Benzyloxy)carbonyl]amino}oxane-4-carboxylic acid;2H-Pyran-4-carboxylic acid, tetrahydro-4-[[(phenylmethoxy)carbonyl]amino]-;MFCD10698084;4-(((benzyloxy)carbonyl)amino)tetrahydro-2H-pyran-4-carboxylic acid;4-{[(benzyloxy)carbonyl]amino}tetrahydro-2H-pyran-4-carboxylic acid;4-([(BENZYLOXY)CARBONYL]AMINO)TETRAHYDRO-2H-PYRAN-4-CARBOXYLIC ACID;4-(Cbz-amino)tetrahydropyran-4-carboxylicAcid;SCHEMBL2704426;DTXSID40598693;KBGZJANMFZSOFP-UHFFFAOYSA-N;AKOS013465808;AB61235;AS-31355;SY022457;DB-367016;4-Cbz-amino-4-tetrahydropyrancarboxylic acid;CS-0345119;EN300-122105;A886247;4-(N-Benzyloxycarbonylamino)-4-carboxytetrahydropyran

Suppliers and Price of 4-(Cbz-amino)tetrahydropyran-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Cbz-Amino)Tetrahydropyran-4-CarboxylicAcid
500mg
$ 285.00

Labseeker
4-([(BENZYLOXY)CARBONYL]AMINO)TETRAHYDRO-2H-PYRAN-4-CARBOXYLICACID 95
5g
$ 2017.00

Crysdot
4-(CBZ-AMINO)TETRAHYDROPYRAN-4-CARBOXYLICACID 95+%
5g
$ 612.00

Chemenu
4-(((benzyloxy)carbonyl)amino)tetrahydro-2H-pyran-4-carboxylicacid 95%
5g
$ 578.00

Apolloscientific
4-Cbz-amino-4-tetrahydropyrancarboxylicacid 97%
1g
$ 270.00

Apolloscientific
4-Cbz-amino-4-tetrahydropyrancarboxylicacid 97%
500mg
$ 180.00

American Custom Chemicals Corporation
4-([(BENZYLOXY)CARBONYL]AMINO)TETRAHYDRO-2H-PYRAN-4-CARBOXYLIC ACID 95.00%
5MG
$ 502.22

Alichem
4-(Cbz-Amino)tetrahydropyran-4-carboxylicacid
5g
$ 624.18

AK Scientific
4-(Cbz-amino)tetrahydropyran-4-carboxylicacid
5g
$ 894.00

Acrotein
4-Cbz-amino-4-tetrahydropyrancarboxylicacid 97%
1g
$ 165.00

Total 8 raw suppliers

Chemical Property of 4-(Cbz-amino)tetrahydropyran-4-carboxylic acid

Chemical Property:

PSA：84.86000
LogP:1.93750
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:279.11067264
Heavy Atom Count:20
Complexity:346

Purity/Quality:

97% ^*data from raw suppliers

4-(Cbz-Amino)Tetrahydropyran-4-CarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCC1(C(=O)O)NC(=O)OCC2=CC=CC=C2

Technology Process of 4-(Cbz-amino)tetrahydropyran-4-carboxylic acid

There total 6 articles about 4-(Cbz-amino)tetrahydropyran-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1379328-03-6
C₆H₁₀NO₃^(1-)*K⁽¹⁺⁾

: 501-53-1,94274-21-2
benzyl chloroformate

: 138402-13-8
4-{[(benzyloxy)carbonyl]amino}oxane-4-carboxylic acid

Guidance literature:: C₆H₁₀NO₃^(1-)*K⁽¹⁺⁾; benzyl chloroformate; In water; acetone; at 0 - 20 ℃;

With hydrogenchloride; In water; pH=1;

Reference yield:

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 138402-13-8
4-{[(benzyloxy)carbonyl]amino}oxane-4-carboxylic acid

Guidance literature:: With sodium chloride; N-ethyl-N,N-diisopropylamine; In water; ethyl acetate; acetonitrile;

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 138402-13-8
4-{[(benzyloxy)carbonyl]amino}oxane-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol; water / 18 h / 60 °C

2.1: potassium hydroxide; water / 66 h / 100 °C

2.2: 0 - 20 °C

2.3: pH 1

With water; potassium hydroxide; In ethanol; water;