Technology Process of 2-Naphthalenecarboxylic acid, 1-bromo-, 3,5-dimethylphenyl ester
There total 5 articles about 2-Naphthalenecarboxylic acid, 1-bromo-, 3,5-dimethylphenyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; dicyclohexyl-carbodiimide;
In
dichloromethane;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.15227/orgsyn.079.0072
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 2-methyl-but-2-ene; sodium chlorite; sodium dihydrogen phosphate monohydrate / water; tert-butyl alcohol / 24 h / 20 °C / Inert atmosphere
2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere
2.2: trialkylamine / 3 h / 20 °C / Inert atmosphere
With
sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane; water; tert-butyl alcohol;
DOI:10.1002/anie.201711126
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: phosphorus tribromide / chloroform / 2 h / 0 °C
1.2: 2 h / 0 - 70 °C
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / Reflux
3.1: 2-methyl-but-2-ene; sodium chlorite; sodium dihydrogenphosphate / tert-butyl alcohol; water / 24 h / 20 °C
4.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 0 - 20 °C
4.2: 3 h / 20 °C
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; oxalyl dichloride; phosphorus tribromide; N,N-dimethyl-formamide; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
dichloromethane; chloroform; water; toluene; tert-butyl alcohol;
DOI:10.1021/acs.orglett.8b02785
