Pentanoic acid, 1-phenylethyl ester, (R)-

Base Information

• Chemical Name: Pentanoic acid, 1-phenylethyl ester, (R)-
• CAS No.: 138457-63-3
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Mol file: 138457-63-3.mol

Synonyms:

Chemical Property of Pentanoic acid, 1-phenylethyl ester, (R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pentanoic acid, 1-phenylethyl ester, (R)-

There total 7 articles about Pentanoic acid, 1-phenylethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-Phenylethanol (98-85-1,13323-81-4) + p-chlorophenyl pentanoate (104316-32-7) → (R)-1-phenylethyl pentanoate (138457-63-3)

Guidance literature:

With Novozym 435; sulphate-doped anatase; In toluene; at 40 ℃; for 10h; Resolution of racemate; Enzymatic reaction;

DOI:10.1016/j.tetlet.2013.07.016

Reference yield:

1-Phenylethanol (98-85-1,13323-81-4) + valeric acid (109-52-4) → (S)-1-phenylethanol (1445-91-6) + (R)-1-phenylethanol (1517-69-7) + (R)-1-phenylethyl pentanoate (138457-63-3)

Guidance literature:

With Lipozyme CaLB-L immobilized on silica gel; In hexane; at 37 ℃; for 48h; Reagent/catalyst; enantioselective reaction; Green chemistry; Enzymatic reaction;

DOI:10.21577/0103-5053.20160277

Reference yield:

1-Phenylethanol (98-85-1,13323-81-4) + isopropenyl valerate (69638-96-6) → (R)-1-phenylethanol (1517-69-7) + (R)-1-phenylethyl pentanoate (138457-63-3) + (S)-1-phenylethyl pentanoate

Guidance literature:

With polyoxyethylene ⁽¹⁰⁾ cetyl ether; n-octyl β-D-glucopyranoside; subtilisin Carlsberg; dicarbonyl(chloro)(η⁵-pentaphenylcyclopentadienyl)ruthenium(II); sodium carbonate; In tetrahydrofuran; at 20 ℃; for 17h; Title compound not separated from byproducts;

DOI:10.1002/chem.200500758

upstream raw materials:

1-Phenylethanol

3-Valeryloxypyridine

ethyl n-valerate

isopropenyl valerate