5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine

Base Information

Chemical Name:5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine
CAS No.:138469-76-8
Molecular Formula:C9H10N2O
Molecular Weight:162.18800
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40569681
Nikkaji Number:J3.559.271G
Wikidata:Q72517054
Mol file:138469-76-8.mol

Synonyms:5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine;138469-76-8;1H-Pyrrolo[3,2-b]pyridine, 5-methoxy-3-methyl-;5-METHOXY-3-METHYL-4-AZAINDOLE;SCHEMBL3219741;AMY9783;DTXSID40569681;VMULISRTALNYDG-UHFFFAOYSA-N;MFCD11848726;AKOS022171745;DS-2988;CS-0082369;A886230

Suppliers and Price of 5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine >95%
1g
$ 1224.00

Labseeker
5-methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine 95
5g
$ 1550.00

Crysdot
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine 97%
5g
$ 317.00

Chemenu
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine 95%+
1g
$ 122.00

Chemenu
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine 95%+
5g
$ 299.00

American Custom Chemicals Corporation
5-METHOXY-3-METHYL-1H-PYRROLO[3,2-B]PYRIDINE 95.00%
5MG
$ 498.48

Alichem
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine
5g
$ 574.69

Alichem
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine
1g
$ 205.20

AK Scientific
5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine
5g
$ 482.00

AccelPharmtech
5-methoxy-3-methyl-1H-Pyrrolo[3,2-b]pyridine 97.00%
25G
$ 4010.00

Total 21 raw suppliers

Chemical Property of 5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine

Chemical Property:

Melting Point:88℃
PSA：37.91000
LogP:1.87990
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.079312947
Heavy Atom Count:12
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CNC2=C1N=C(C=C2)OC

Technology Process of 5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine

There total 4 articles about 5-Methoxy-3-methyl-1H-pyrrolo[3,2-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 138469-68-8
2-(6-methoxy-3-nitropyridin-2-yl)propanenitrile

: 138469-76-8
3-methylpyrrolo<3,2-b>pyridinee

Guidance literature:: With hydrogen; In methanol; at 20 ℃; for 36h; under 760.051 Torr;
DOI:10.1021/acs.orglett.6b02659

Reference yield: 72.0%

: 4744-08-5
1,1-diethoxypropane

: 1338466-39-9
di-tert-butyl 1-(6-methoxypyridin-3-yl)hydrazine-1,2-dicarboxylate

: 138469-76-8
3-methylpyrrolo<3,2-b>pyridinee

Guidance literature:: 1,1-diethoxypropane; di-tert-butyl 1-(6-methoxypyridin-3-yl)hydrazine-1,2-dicarboxylate; With sulfuric acid; In water; for 1h; Reflux; Inert atmosphere;

With sodium carbonate; In water; Saturated solution; Inert atmosphere;
DOI:10.1021/jo201866c

Reference yield:

: 111795-99-4
2-(6-methoxy-3-nitropyridin-2-yl)acetonitrile

: 138469-76-8
3-methylpyrrolo<3,2-b>pyridinee

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) PPh₃, DEAD / 1.) THF, 0 deg C, 5 min, 2.) THF, 0 deg C, 34 min

2: 16 percent / H₂ / 10percent Pd/C / butan-1-ol

With hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In butan-1-ol;