Chemical Property of GTS-21 dihydrochloride
Chemical Property:
- Vapor Pressure:4.11E-09mmHg at 25°C
- Melting Point:216-217℃ (decomposition)
- Boiling Point:485.6°C at 760 mmHg
- Flash Point:247.5°C
- PSA：43.71000
- LogP:3.20090
- Storage Temp.:2-8°C
- Solubility.:H2O: >5mg/mL
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:4
- Exact Mass:380.1058333
- Heavy Atom Count:25
- Complexity:447
- Purity/Quality:
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98%,99%, *data from raw suppliers
GTS21Dihydrochloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:COC1=CC(=C(C=C1)C=C2CCCN=C2C3=CN=CC=C3)OC.Cl.Cl
- Isomeric SMILES:COC1=CC(=C(C=C1)/C=C/2\CCCN=C2C3=CN=CC=C3)OC.Cl.Cl
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Uses
GTS-21 has been used:as an α7 nicotinic acetylcholine receptors (nAChR) partial agonist to elucidate its anti-inflammatory effects in mouse macrophagesto test its protective effect on the renal injury induced by lipopolysaccharide (LPS) to test its effect on microvascular inflammation?in endotoxemia induced by LPS
