N-Carboxybenzyl GeMcitabine

Base Information

Chemical Name:N-Carboxybenzyl GeMcitabine
CAS No.:138685-83-3
Molecular Formula:C17H17F2N3O6
Molecular Weight:397.335
Hs Code.:
Mol file:138685-83-3.mol

Synonyms:N-Carboxybenzyl Gemcitabine;N-CBZ GEMCITABINE;

Suppliers and Price of N-Carboxybenzyl GeMcitabine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Carboxybenzyl Gemcitabine
10mg
$ 425.00

Usbiological
N-Carboxybenzyl Gemcitabine
5mg
$ 496.00

TRC
N-CarboxybenzylGemcitabine
25mg
$ 425.00

Biosynth Carbosynth
N-Cbz gemcitabine
100 mg
$ 1911.00

Biosynth Carbosynth
N-Cbz gemcitabine
50 mg
$ 1051.50

Biosynth Carbosynth
N-Cbz gemcitabine
25 mg
$ 578.50

Biosynth Carbosynth
N-Cbz gemcitabine
5 mg
$ 174.90

Total 9 raw suppliers

Chemical Property of N-Carboxybenzyl GeMcitabine

Chemical Property:

Melting Point:>115°C (dec.)
PSA：122.91000
LogP:0.95090
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

N-Carboxybenzyl Gemcitabine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Gemcitabine (G305000) derivative.

Technology Process of N-Carboxybenzyl GeMcitabine

There total 11 articles about N-Carboxybenzyl GeMcitabine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1613293-13-2
4-(benzyloxycarbonylamino)-1-(2-deoxy-2,2-difluoro-5-O-[tertbutyl(dimethyl)silyl]-β-D-erythro-pentofuranosyl)pyrimidin-2(1H)-one

: 138685-83-3
4-(benzyloxycarbonylamino)-1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)pyrimidin-2(1H)-one

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1021/jm500531z

Reference yield: 91.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 95058-81-4,103882-85-5
gemcitabine

: 138685-83-3
4-(benzyloxycarbonylamino)-1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)pyrimidin-2(1H)-one

Guidance literature:: gemcitabine; With pyridine; chloro-trimethyl-silane; at 4 - 20 ℃; for 1.5h; Inert atmosphere;

benzyl chloroformate; In methanol; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2019.08.003