Betuletol

Base Information

Chemical Name:Betuletol
CAS No.:35214-88-1
Molecular Formula:C17H14 O7
Molecular Weight:330.294
Hs Code.:
NSC Number:641548
DSSTox Substance ID:DTXSID70420059
Nikkaji Number:J487.482J
Wikidata:Q82231318
Metabolomics Workbench ID:25954
ChEMBL ID:CHEMBL311155
Mol file:35214-88-1.mol

Synonyms:Betuletol;NSC641548;6,4'-Dimethoxy-3,5,7-trihydroxyflavone;35214-88-1;Beturetol;Oprea1_748279;CHEMBL311155;DTXSID70420059;LMPK12112871;NSC-641548;NCI60_014067

Suppliers and Price of Betuletol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Betuletol

Chemical Property:

Vapor Pressure:9.54E-15mmHg at 25°C
Boiling Point:589.6°Cat760mmHg
Flash Point:220.4°C
Density:1.507g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:330.07395278
Heavy Atom Count:24
Complexity:509

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(C(=O)C3=C(O2)C=C(C(=C3O)OC)O)O

Technology Process of Betuletol

There total 14 articles about Betuletol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 188927-57-3
7-Benzyloxy-3,5-dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chromen-4-one

: 35214-88-1
betuletol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; Ambient temperature;
DOI:10.1248/cpb.45.446

Reference yield:

: 3162-51-4
1-(2,4-Bis-benzyloxy-3,6-dimethoxy-phenyl)-ethanone

: 35214-88-1
betuletol

Guidance literature:: Multi-step reaction with 11 steps

1: 100 percent / conc. HCl, acetic acid / 1 h / Ambient temperature

2: 83 percent / K₂CO₃, KI / acetone; dimethylformamide / Heating

3: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 °C

4: pyridine / 2 h / 70 - 80 °C

5: KOH / pyridine / 80 °C

6: 87 percent / conc. H₂SO₄, acetic acid / 1 h / 50 °C

7: 71 percent / dimethyldioxirane / acetone / 0 °C

8: 96 percent / K₂CO₃ / acetone / Heating

9: 91 percent / AlCl₃ / acetonitrile / 0.5 h / Ambient temperature

10: 90 percent / K₂CO₃ / methanol / 1.5 h / Heating

11: 90 percent / H₂ / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature

With pyridine; hydrogenchloride; potassium hydroxide; aluminium trichloride; aluminum tri-bromide; sulfuric acid; hydrogen; 3,3-dimethyldioxirane; potassium carbonate; acetic acid; potassium iodide; sodium iodide; palladium on activated charcoal; In pyridine; methanol; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1248/cpb.45.446

Reference yield:

: 3162-52-5
1-(4-benzyloxy-2-hydroxy-3,6-dimethoxy-phenyl)-ethanone

: 35214-88-1
betuletol

Guidance literature:: Multi-step reaction with 10 steps

1: 83 percent / K₂CO₃, KI / acetone; dimethylformamide / Heating

2: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 °C

3: pyridine / 2 h / 70 - 80 °C

4: KOH / pyridine / 80 °C

5: 87 percent / conc. H₂SO₄, acetic acid / 1 h / 50 °C

6: 71 percent / dimethyldioxirane / acetone / 0 °C

7: 96 percent / K₂CO₃ / acetone / Heating

8: 91 percent / AlCl₃ / acetonitrile / 0.5 h / Ambient temperature

9: 90 percent / K₂CO₃ / methanol / 1.5 h / Heating

10: 90 percent / H₂ / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature

With pyridine; potassium hydroxide; aluminium trichloride; aluminum tri-bromide; sulfuric acid; hydrogen; 3,3-dimethyldioxirane; potassium carbonate; acetic acid; potassium iodide; sodium iodide; palladium on activated charcoal; In pyridine; methanol; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1248/cpb.45.446