2,5-Dimethyl-1-phenylphospholane

Base Information

• Chemical Name: 2,5-Dimethyl-1-phenylphospholane
• CAS No.: 40358-68-7
• Molecular Formula: C12H17P
• Molecular Weight: 192.2371
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID40960775
• Nikkaji Number: J1.276.145G
• Mol file: 40358-68-7.mol

Synonyms:40358-68-7;2,5-dimethyl-1-phenylphospholane;Phospholane,2,5-dimethyl-1-phenyl-;Phospholane, 2,5-dimethyl-1-phenyl-;SCHEMBL3688631;DTXSID40960775

Chemical Property of 2,5-Dimethyl-1-phenylphospholane

Chemical Property:

• Vapor Pressure: 0.00909mmHg at 25°C
• Boiling Point: 274.4°Cat760mmHg
• Flash Point: 124.1°C
• PSA: 13.59000
• Density: g/cm³
• LogP: 3.36460
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 192.106787540
• Heavy Atom Count: 13
• Complexity: 151

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1CCC(P1C2=CC=CC=C2)C

Technology Process of 2,5-Dimethyl-1-phenylphospholane

There total 4 articles about 2,5-Dimethyl-1-phenylphospholane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methylpent-4-enylphenylphosphine (262593-99-7) → 2,5-dimethyl-1-phenylphospholane (40358-68-7)

Guidance literature:

With (pentamethylcyclopentadienyl)2LaCH(TMS)2; In benzene-d6; at -78 - 22 ℃;

DOI:10.1021/ja010811i

Reference yield:

1-methylpent-4-en-1-yl methanesulfonate (89122-07-6) → 2,5-dimethyl-1-phenylphospholane (40358-68-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / tetrahydrofuran / 1.5 h

2: 20 percent / Li / tetrahydrofuran / 2.5 h

3: Cp'2LaCH(TMS)2 / benzene-d6 / -78 - 22 °C

With (pentamethylcyclopentadienyl)2LaCH(TMS)2; lithium; In tetrahydrofuran; benzene-d6;

DOI:10.1021/ja010811i

Reference yield:

potassium diphenylphosphine (15475-27-1,4346-39-8) → 2,5-dimethyl-1-phenylphospholane (40358-68-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / tetrahydrofuran / 1.5 h

2: 20 percent / Li / tetrahydrofuran / 2.5 h

3: Cp'2LaCH(TMS)2 / benzene-d6 / -78 - 22 °C

With (pentamethylcyclopentadienyl)2LaCH(TMS)2; lithium; In tetrahydrofuran; benzene-d6;

DOI:10.1021/ja010811i

upstream raw materials:

1-methylpent-4-enylphenylphosphine

1-methylpent-4-en-1-yl methanesulfonate

potassium diphenylphosphine

1-methylpent-4-enyldiphenylphosphine

Downstream raw materials:

[ClRh(CO)(2,4-dimethyl-1-phenylphosphetane)2]