4Bromo-4-NitroChalcone

Base Information

• Chemical Name: 4Bromo-4-NitroChalcone
• CAS No.: 13909-51-8
• Molecular Formula: C15H10BrNO3
• Molecular Weight: 332.153
• Mol file: 13909-51-8.mol

Synonyms:4-Bromo-4'-nitrochalcon;4-bromo-4'-nitrochalcone;2-Propen-1-one,3-(4-bromophenyl)-1-(4-nitrophenyl);

Chemical Property of 4Bromo-4-NitroChalcone

Chemical Property:

• PSA: 62.89000
• LogP: 4.77660

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-BROMO-4'-NITROCHALCONE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4Bromo-4-NitroChalcone

There total 6 articles about 4Bromo-4-NitroChalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-bromo-benzaldehyde (1122-91-4) + (4-nitrophenyl)ethanone (100-19-6) → 3-(4-bromophenyl)-1-(4-nitrophenyl)prop-2-en-1-one (13909-51-8)

Guidance literature:

With sodium hydroxide; In ethanol; at 5 - 10 ℃;

DOI:10.1007/s00044-012-0385-3

Reference yield: 63.0%

4-{[1-(4-Bromo-phenyl)-meth-(E)-ylidene]-amino}-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one (61098-05-3) + (4-nitrophenyl)ethanone (100-19-6) → 3-(4-bromophenyl)-1-(4-nitrophenyl)prop-2-en-1-one (13909-51-8)

Guidance literature:

With hydrogenchloride; In benzene; for 3h; heating on water bath;

Reference yield: 57.0%

2-(4-bromo-benzylidenamino)-ethanol (27895-60-9) + (4-nitrophenyl)ethanone (100-19-6) → 3-(4-bromophenyl)-1-(4-nitrophenyl)prop-2-en-1-one (13909-51-8)

Guidance literature:

With hydrogenchloride; In ethanol; for 12h; Heating;

upstream raw materials:

2-(4-bromo-benzylidenamino)-ethanol

(4-nitrophenyl)ethanone

4-{[1-(4-Bromo-phenyl)-meth-(E)-ylidene]-amino}-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one

4-bromo-benzaldehyde

Downstream raw materials:

(E)-1-(4-aminophenyl)-3-(4-bromophenyl)-2-propen-1-one