2-Methyl-3,3,4,4-tetrafluoro-2-butanol

Base Information

• Chemical Name: 2-Methyl-3,3,4,4-tetrafluoro-2-butanol
• CAS No.: 29553-26-2
• Molecular Formula: C5H8 F4 O
• Molecular Weight: 160.112
• Hs Code.: 2905590090
• European Community (EC) Number: 249-692-8
• NSC Number: 86110
• UNII: 0XK3480CJR
• DSSTox Substance ID: DTXSID9022283
• Nikkaji Number: J25.042B
• Wikidata: Q27231227
• Mol file: 29553-26-2.mol

Synonyms:29553-26-2;2-Methyl-3,3,4,4-tetrafluoro-2-butanol;3,3,4,4-Tetrafluoro-2-methylbutan-2-ol;2,2,3,3-Tetrafluoro-1,1-dimethylpropanol;2-Butanol, 3,3,4,4-tetrafluoro-2-methyl-;3,3,4,4-Tetrafluoro-2-methyl-2-butanol;EINECS 249-692-8;NSC 86110;BRN 1815827;UNII-0XK3480CJR;0XK3480CJR;2-BUTANOL, 2-METHYL-3,3,4,4-TETRAFLUORO-;NSC-86110;2-Methyl-3.3.4.4-tetrafluoro-2-butanol;2,2,3,3-TETRAFLURO-1,1-DIMTHYLPROPANOL;NSC86110;C5H8F4O;SCHEMBL5426428;DTXSID9022283;C5-H8-F4-O;CCG-40565;MFCD00044326;AKOS006228447;2-Methyl-3,4,4-tetrafluoro-2-butanol;2,3,3-Tetrafluoro-1,1-dimethylpropanol;2-Butanol,3,4,4-tetrafluoro-2-methyl-;LS-46582;1,1,2,2-Tetrafluoro-3-methyl-3-butanol;FT-0638858;3,3,4,4-Tetrafluoro-2-methyl-2-butanol #;1,1-dimethyl-2,2,3,3-tetrafluoro-1-propanol;EN300-1930422;Q27231227;(4-Methylpiperazin-1-yl)piperidin-4-yl-methanonedi hydrochloride

Chemical Property of 2-Methyl-3,3,4,4-tetrafluoro-2-butanol

Chemical Property:

• Vapor Pressure: 1.25mmHg at 25°C
• Boiling Point: 153.2°Cat760mmHg
• Flash Point: 73.9°C
• PSA: 20.23000
• Density: 1.223g/cm³
• LogP: 1.65770
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 160.05112752
• Heavy Atom Count: 10
• Complexity: 121

Purity/Quality:

99% ^*data from raw suppliers

2,2,3,3-TETRAFLUORO-1,1-DIMETHYLPROPANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C(C(F)F)(F)F)O

Technology Process of 2-Methyl-3,3,4,4-tetrafluoro-2-butanol

There total 2 articles about 2-Methyl-3,3,4,4-tetrafluoro-2-butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) + isopropyl alcohol (67-63-0,8013-70-5) → 3,3,4,4-tetrafluoro-2-methyl-2-butanol (29553-26-2)

Guidance literature:

With di-tert-butyl peroxide; at 140 ℃; for 30h; under 7600.51 Torr;

DOI:10.1134/S1070427207030123

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) + isopropyl alcohol (67-63-0,8013-70-5) → 3,3,4,4-tetrafluoro-2-methyl-2-butanol (29553-26-2) + α,α-dimethyl-ω-hydroperfluoropentanol (2673-15-6)

Guidance literature:

With acetone; at -30 ℃; for 8h; Irradiation; various initiators, times, temp.;

DOI:10.1016/S0022-1139(00)83928-7

Reference yield: 47.0%

3,3,4,4-tetrafluoro-2-methyl-2-butanol (29553-26-2) → 2-Methyl-1,1,4-trihydro-tetrafluor-1-buten (57252-78-5)

Guidance literature:

With 1,1,2,2-tetrafluoro-N,N-dimethylethan-1-amine; at 100 ℃; for 1h;

DOI:10.1016/S0022-1139(01)00372-4

upstream raw materials:

polytetrafluoroethylene

isopropyl alcohol

Downstream raw materials:

2-Methyl-1,1,4-trihydro-tetrafluor-1-buten