(4-Ethylphenyl)(hydroxy)acetic acid

Base Information

Chemical Name:(4-Ethylphenyl)(hydroxy)acetic acid
CAS No.:10408-52-3
Molecular Formula:C10H12 O3
Molecular Weight:180.203
Hs Code.:
NSC Number:126598
DSSTox Substance ID:DTXSID00298864

Synonyms:(4-ethylphenyl)(hydroxy)acetic acid;2-(4-ethylphenyl)-2-hydroxyacetic acid;10408-52-3;Benzeneacetic acid,4-ethyl-a-hydroxy-;NSC126598;SCHEMBL11476703;DTXSID00298864;MFCD14602005;AKOS005265480;NSC-126598;BS-12639;CS-0296617;F83542;EN300-1229088

Suppliers and Price of (4-Ethylphenyl)(hydroxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (4-Ethylphenyl)(hydroxy)acetic acid

Chemical Property:

Vapor Pressure:1.98E-05mmHg at 25°C
Boiling Point:347.8°Cat760mmHg
Flash Point:178.3°C
Density:1.217g/cm³
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:180.078644241
Heavy Atom Count:13
Complexity:171

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC=C(C=C1)C(C(=O)O)O

Technology Process of (4-Ethylphenyl)(hydroxy)acetic acid

There total 6 articles about (4-Ethylphenyl)(hydroxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-41-4,27536-89-6
ethylbenzene

: 609-09-6
Diethyl ketomalonate

: 10408-52-3
(rac)-2-(4-ethylphenyl)-2-hydroxyacetic acid

Guidance literature:: With tin(IV) chloride; Erwaermen des Reaktionsprodukts mit wss. Kalilauge und Erwaermen der mit wss. Salzsaeure angesaeuerten Reaktionsloesung;
DOI:10.1021/ja01272a008

Reference yield:

: 937-30-4
4-ethylacetophenone

: 10408-52-3
(rac)-2-(4-ethylphenyl)-2-hydroxyacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; selenium(IV) oxide / 12 h / 110 °C / Inert atmosphere

2: palladium 10% on activated carbon; triphenylphosphine; sodium acetate; hydrogen / methanol / 20 °C / 7500.75 Torr

With pyridine; selenium(IV) oxide; palladium 10% on activated carbon; hydrogen; sodium acetate; triphenylphosphine; In methanol;
DOI:10.1002/adsc.201700846

Reference yield:

: 7099-89-0
2-(4-ethylphenyl)-2-oxoacetic acid

: 10408-52-3
(rac)-2-(4-ethylphenyl)-2-hydroxyacetic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; sodium acetate; triphenylphosphine; In methanol; at 20 ℃; under 7500.75 Torr;
DOI:10.1002/adsc.201700846