Xanomeline oxalate

Base Information

Chemical Name:Xanomeline oxalate
CAS No.:141064-23-5
Molecular Formula:C14H23N3OS.C2H2O4
Molecular Weight:371.45200
Hs Code.:
UNII:JF5A0PK3G5
ChEMBL ID:CHEMBL73149
DSSTox Substance ID:DTXSID90596482
Wikidata:Q27281485
Mol file:141064-23-5.mol

Synonyms:XANOMELINE OXALATE;141064-23-5;Xanomeline (oxalate);Xanomelineoxalate;Xanomeline oxalate [MI];LY246708 (oxalate);JF5A0PK3G5;CHEMBL73149;3-(Hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole oxalate;3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole;oxalic acid;Pyridine, 3-(4-(hexyloxy)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methyl-, ethanedioate (1:1);Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-, ethanedioate (1:1);UNII-JF5A0PK3G5;SCHEMBL6911783;DTXSID90596482;BCP11070;MFCD12828778;AKOS024457691;AKOS025243722;3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate;HY-13410;MS-25988;A910997;J-007454;Q27281485;3-[4-(Hexyloxy)-1,2,5-thiadiazol-3- yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate;Oxalic acid--5-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1-methyl-1,2,3,6-tetrahydropyridine (1/1)

Suppliers and Price of Xanomeline oxalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Xanomeline oxalate
10mg
$ 438.00

TRC
XanomelineOxalate
25mg
$ 275.00

Tocris
Xanomelineoxalate ≥98%(HPLC)
50
$ 796.00

Tocris
Xanomelineoxalate ≥98%(HPLC)
10
$ 195.00

Sigma-Aldrich
Xanomeline Oxalate - CAS 141064-23-5 - Calbiochem
10 mg
$ 147.00

Sigma-Aldrich
Xanomeline Oxalate - CAS 141064-23-5 - Calbiochem
5058160001
$ 142.00

DC Chemicals
Xanomeline(oxalate) >98%
1 g
$ 2600.00

DC Chemicals
Xanomeline(oxalate) >98%
250 mg
$ 1300.00

Crysdot
Xanomelineoxalate 98+%
10mg
$ 141.00

Crysdot
Xanomelineoxalate 98+%
5mg
$ 79.00

Total 12 raw suppliers

Chemical Property of Xanomeline oxalate

Chemical Property:

Melting Point:148-150℃
PSA：141.09000
LogP:2.30960
Storage Temp.:Desiccate at +4°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:371.15149208
Heavy Atom Count:25
Complexity:370

Purity/Quality:

97% ^*data from raw suppliers

Xanomeline oxalate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCOC1=NSN=C1C2=CCCN(C2)C.C(=O)(C(=O)O)O
Description Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline (oxalate) is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline (oxalate), enhance memory function and has utility in treating Alzheimer’s Disease.
Uses Xanomeline oxalate is a functionally selective mAChR M1 agonist.

Technology Process of Xanomeline oxalate

There total 3 articles about Xanomeline oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 131988-19-7
3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

: 141064-23-5
Xanomeline oxalate

Guidance literature:: With sodium tetrahydroborate; In ethanol; water;

Reference yield:

: 131986-28-2
3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine

: 141064-23-5
Xanomeline oxalate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium / water; hexan-1-ol

2: acetone

3: sodium borohydrid / ethanol; water; acetone

With sodium borohydrid; sodium; In ethanol; water; acetone; hexan-1-ol;

Reference yield:

: 131987-69-4
3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)pyridine

: 141064-23-5
Xanomeline oxalate

Guidance literature:: Multi-step reaction with 2 steps

1: acetone

2: sodium borohydrid / ethanol; water; acetone

With sodium borohydrid; In ethanol; water; acetone;