5-Chloro-2-phenylthiazole

Base Information

Chemical Name:5-Chloro-2-phenylthiazole
CAS No.:141305-41-1
Molecular Formula:C9H6ClNS
Molecular Weight:195.672
Hs Code.:
DSSTox Substance ID:DTXSID90565855
Wikidata:Q82451163
Mol file:141305-41-1.mol

Synonyms:5-CHLORO-2-PHENYLTHIAZOLE;141305-41-1;5-Chloro-2-phenyl-1,3-thiazole;SCHEMBL2430081;DTXSID90565855

Suppliers and Price of 5-Chloro-2-phenylthiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-Chloro-2-phenylthiazole

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:194.9909481
Heavy Atom Count:12
Complexity:148

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC=C(S2)Cl

Technology Process of 5-Chloro-2-phenylthiazole

There total 5 articles about 5-Chloro-2-phenylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1826-11-5
2-phenylthiazole

: 141305-41-1
5-chloro-2-phenylthiazole

Guidance literature:: 2-phenylthiazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

With hexachloroethane; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h;
DOI:10.1021/jo902515z

Reference yield: 85.0%

: (4-chloro-2-phenyl-4-thiazolyl)triphenylphosphonium perchlorate

: 141305-41-1
5-chloro-2-phenylthiazole

Guidance literature:: With sodium hydroxide; In methanol; at 40 - 50 ℃; for 0.0833333h;

Reference yield:

: (2,2-Dichloro-1-{[1-chloro-1-phenyl-meth-(Z)-ylidene]-amino}-vinyl)-triphenyl-phosphonium; chloride

: 141305-41-1
5-chloro-2-phenylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 1.) thiourea, 2.) aq. NaClO₄ / acetonitrile / 4 h / Heating

2: 85 percent / aq. NaOH / methanol / 0.08 h / 40 - 50 °C

With sodium hydroxide; sodium perchlorate; thiourea; In methanol; acetonitrile;