Benzenepentanoic acid, b-hydroxy-, phenyl ester, (R)-

Base Information

• Chemical Name: Benzenepentanoic acid, b-hydroxy-, phenyl ester, (R)-
• CAS No.: 141339-06-2
• Molecular Formula: C₁₇H₁₈O₃
• Molecular Weight: 270.328
• Mol file: 141339-06-2.mol

Synonyms:

Chemical Property of Benzenepentanoic acid, b-hydroxy-, phenyl ester, (R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepentanoic acid, b-hydroxy-, phenyl ester, (R)-

There total 2 articles about Benzenepentanoic acid, b-hydroxy-, phenyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + 1-phenoxy-1-trimethylsilyloxyethene (111061-31-5) → (R)-3-Hydroxy-5-phenyl-pentanoic acid phenyl ester (141339-06-2) + (S)-3-Hydroxy-5-phenyl-pentanoic acid phenyl ester (141339-06-2)

Guidance literature:

With hydrogenchloride; borane; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, -78 deg C, 2.) THF;

DOI:10.1016/S0040-4039(00)91717-9

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + 1-phenoxy-1-trimethylsilyloxyethene (111061-31-5) → (R)-3-Hydroxy-5-phenyl-pentanoic acid phenyl ester (141339-06-2) + (S)-3-Hydroxy-5-phenyl-pentanoic acid phenyl ester (141339-06-2)

Guidance literature:

With hydrogenchloride; borane; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, -78 deg C, 2.) THF;

DOI:10.1016/S0040-4039(00)91717-9

upstream raw materials:

3-phenyl-propionaldehyde

1-phenoxy-1-trimethylsilyloxyethene