2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile

Base Information

Chemical Name:2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile
CAS No.:21680-48-8
Molecular Formula:C₁₃H₁₂F₃N₃O₂
Molecular Weight:299.252
Hs Code.:
NSC Number:103189
DSSTox Substance ID:DTXSID30944286
ChEMBL ID:CHEMBL2144773
Mol file:21680-48-8.mol

Synonyms:21680-48-8;NSC103189;MLS002703764;2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile;NSC 103189;2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro(5.5)undecane-1,5-dicarbonitrile;NCIOpen2_007257;CHEMBL2144773;DTXSID30944286;8,10-dioxo-4-(trifluoromethyl)-9-azaspiro[5.5]undecane-7,11-dicarbonitrile;NSC-103189;SMR001570479;2-Hydroxy-4-oxo-8-(trifluoromethyl)-3-azaspiro[5.5]undec-2-ene-1,5-dicarbonitrile

Suppliers and Price of 2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile

Chemical Property:

Vapor Pressure:3.16E-11mmHg at 25°C
Boiling Point:527.8°C at 760 mmHg
Flash Point:273°C
Density:1.4g/cm³
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:299.08816112
Heavy Atom Count:21
Complexity:546

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CC2(C1)C(C(=O)NC(=O)C2C#N)C#N)C(F)(F)F

Technology Process of 2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile

There total 1 articles about 2,4-Dioxo-8-(trifluoromethyl)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21680-48-8
2,4-dioxo-8-trifluoromethyl-3-aza-spiro[5.5]undecane-1,5-dicarbonitrile

Guidance literature:: 3-Trifluormethyl-cyclohexanon, Cyanessigsaeure-ethylester (0grad);
DOI:10.1021/jm00301a032

Reference yield:

: 21680-48-8
2,4-dioxo-8-trifluoromethyl-3-aza-spiro[5.5]undecane-1,5-dicarbonitrile

: 21680-57-9
1,1-Bis-(β-hydroxyaethyl)-3-trifluormethyl-cyclohexan

Guidance literature:: Multi-step reaction with 3 steps

1: (i) H₂SO₄, (ii) H₂O

2: H₂SO₄

3: LiAlH₄

With lithium aluminium tetrahydride; sulfuric acid;
DOI:10.1021/jm00301a032