4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo-

Base Information

Chemical Name:4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo-
CAS No.:172256-00-7
Molecular Formula:C23H26N2O2SSe
Molecular Weight:473.4897
Hs Code.:
DSSTox Substance ID:DTXSID30169235

Synonyms:172256-00-7;4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo-;6-((3,5-Diethylphenyl)selenenyl)-5-methylethyl-1-((phenylmethoxy)methyl)-2-thioxo-1,3-dihydropyrimidin-4-one;4(1H)-Pyrimidinone, 6-[(3,5-dimethylphenyl)seleno]-2,3-dihydro-5-(1-methylethyl)-1-[(phenylmethoxy)methyl]-2-thioxo-;6-[(3,5-Diethylphenyl)selenenyl]-5-methylethyl-1-[(phenylmethoxy)methyl]-2-thioxo-1,3-dihydropyrimidin-4-one;SCHEMBL7533007;DTXSID30169235;1-(benzyloxymethyl)-6-(3,5-dimethylphenyl)selanyl-5-isopropyl-2-thioxo-pyrimidin-4-one

Suppliers and Price of 4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:474.08802
Heavy Atom Count:29
Complexity:620

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)[Se]C2=C(C(=O)NC(=S)N2COCC3=CC=CC=C3)C(C)C)C

Technology Process of 4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo-

There total 3 articles about 4(1H)-Pyrimidinone, 6-((3,5-dimethylphenyl)seleno)-2,3-dihydro-5-(1-methylethyl)-1-((phenylmethoxy)methyl)-2-thioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 144410-22-0
1-[(benzyloxy)methyl]-5-isopropyl-2-thiouracil

: 172256-62-1
1,2-bis(3,5-dimethylphenyl)diselane

: 172256-00-7
1-[(benzyloxy)methyl]-6-[(3,5-dimethylphenyl)selenenyl]-5-isopropyl-2-thiouracil

Guidance literature:

Reference yield:

: 108-69-0
3,5-dimethylaminoaniline

: 172256-00-7
1-[(benzyloxy)methyl]-6-[(3,5-dimethylphenyl)selenenyl]-5-isopropyl-2-thiouracil

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) aq. HCl, NaNO₂, 2.) NaOAc / 1.) 0 deg C, 1 h, 2.) H₂O, 1 h, RT

2: 98 percent / aq. NaOH / ethanol / 3 h / Ambient temperature

3: 1.) LDA / 1.) THF, cyclohexane, 1 h, 2.) THF, cyclohexane, -70 deg C, 1 h

With hydrogenchloride; sodium hydroxide; sodium acetate; lithium diisopropyl amide; sodium nitrite; In ethanol;
DOI:10.1002/jhet.5570330446

Reference yield:

: 183137-77-1
3,5-dimethylphenyl selenocyanate

: 172256-00-7
1-[(benzyloxy)methyl]-6-[(3,5-dimethylphenyl)selenenyl]-5-isopropyl-2-thiouracil

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / aq. NaOH / ethanol / 3 h / Ambient temperature

2: 1.) LDA / 1.) THF, cyclohexane, 1 h, 2.) THF, cyclohexane, -70 deg C, 1 h

With sodium hydroxide; lithium diisopropyl amide; In ethanol;
DOI:10.1002/jhet.5570330446